Dental Implant Loading, Partial Edentulism of the Maxilla, Tooth Loss in the Anterior Maxilla
Conditions
Keywords
Dental Implants, Immediate Loading, Delayed Loading, Maxillary Implants, Anterior Maxilla, Partial Edentulism, Implant Stability, Osseointegration
Brief summary
This interventional comparative clinical study was conducted to evaluate and compare the clinical stability and radiographic outcomes of immediate versus delayed loading of dental implants placed in the anterior region of the maxilla. Immediate loading protocols have been shown to improve oral health-related quality of life and patient satisfaction; however, their influence on implant stability and osseointegration remains an area of ongoing investigation. A total of sixteen dental implants were placed and the participants were randomly allocated into two equal groups using a computer-generated randomization method (www.Randomizer.org). In Group I (control group), eight implants were placed and restored following a delayed loading protocol, with prosthetic loading performed six months after implant placement. In Group II (study group), eight implants were placed and immediately loaded with provisional polymethyl methacrylate (PMMA) restorations. After six months, the provisional restorations were replaced with definitive fixed prostheses. Preoperative planning of implant placement was performed using cone beam computed tomography (CBCT). Clinical evaluation of implant stability was carried out using the Osstell device, while radiographic assessment of peri-implant bone density and marginal bone changes was performed using standardized indirect digital radiographs. Radiographic evaluations were obtained immediately after implant placement and at six months postoperatively. The clinical and radiographic outcomes of both loading protocols were compared to assess implant stability and osseointegration.
Interventions
DEVICEDental Implant
Endosseous dental implants placed in the anterior maxilla and restored using either immediate or delayed loading protocols.
Sponsors
Suez Canal University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Adults aged 20-55 years * Both genders * Healthy individuals (ASA I) without systemic diseases * Patients with one or more missing teeth in the anterior maxilla
Exclusion criteria
* Pregnant or lactating women, or females with osteoporosis * Patients with harmful oral habits such as bruxism or smoking * Poor oral hygiene * Gingival or periodontal diseases with severe vertical or horizontal bone loss * Teeth with periapical or lateral infections or lesions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Implant Stability (ISQ) | Baseline (immediately after implant placement) and 6 months postoperatively | Clinical stability of dental implants was assessed using the Osstell device. The implant stability quotient (ISQ) was measured immediately after implant placement and at 6 months postoperatively. ISQ scores range from 1-100, with scores ≥70 indicating high stability, 60-69 medium stability, and \<60 low stability. |
| Peri-implant Bone Density | Baseline, 3 months, 6 months | Bone density around the implants was measured using standardized direct paralleling digital periapical radiographs and analyzed with IDRISI Kilimanjaro software. Two zones were evaluated: the osseointegration zone near the implant border and the surrounding bone interface. Measurements were recorded immediately postoperatively and at 3 and 6 months. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Pain (Visual Analog Scale, VAS) | 1, 3, and 7 days postoperatively | Patients reported the degree of pain using a 10-cm visual analog scale (VAS), where 0 = no pain and 10 = worst possible pain. Pain was assessed at 1, 3, and 7 days postoperatively. |
| Visual Scale of Edema | 1, 3, and 7 days postoperatively | Facial edema was assessed using a visual grading scale: No edema, Low-grade, Intermediate-grade, and High-grade, based on visual inspection and palpation. Edema was evaluated at 1, 3, and 7 days postoperatively. |
Countries
Egypt
Contacts
STUDY_CHAIRMohamed Said Hamed, Professor
Professor of Oral and Maxillofacial Surgery, Faculty of Dentistry - Suez Canal University
STUDY_DIRECTORAsmaa Yousri Abdallah, Assistant professor
Assistant professor of Oral Radiology, Faculty of Dentistry
STUDY_DIRECTORAhmed Abd elmohsen Younis, Assistant professor
Assistant Professor of Oral and Maxillofacial Surgery, Faculty of Dentistry - Suez Canal University
Outcome results
None listed