Evaluatıon of TREM-1, MMP-8 and TIMP-1 Levels in Perı-Implant Crevicular Fluıd of Perı-Implanted Indıvıduals

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07379892

Enrollment

Registered

2026-02-02

Start date

2023-06-01

Completion date

2024-05-20

Last updated

2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periimplantitis

Keywords

periimplantitis, TREM-1, MMP-8, TIMP-1

Brief summary

The aim of this study was to evaluate the relationship between Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1), Matrix Metalloproteinases-8 (MMP-8) and Tissue Inhibitors of Metalloproteinases-1 (TIMP-1) levels in peri-implant crevicular fluid (PICF) in peri-implantitis patients.

Detailed description

The aim of this study was to evaluate the relationship between TREM-1, MMP-8 and TIMP-1 levels in peri-implant crevicular fluid (PICF) in patients with peri-implantitis, and the correlation of these markers with clinical periodontal parameters.

Interventions

OTHERCollection of PICF samples

TREM-1, MMP-8 and TIPM-1 levels reseach in PICF samples

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* Systemically healthy * Pregnancy or lactation

Exclusion criteria

* osteoporosis * rheumatoid arthritis * autoimmune disease * diabetes

Design outcomes

Primary

Measure	Time frame	Description
TREM-1, MMP-8 and TIMP-1 levels in PICF samples	1 month	TREM-1, MMP-8, and TIMP-1 levels in PICF samples were measured by ELISA method

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 10, 2026