Cesarean Section Pain, Diclofenac, Suppository, Postoperative Pain
Conditions
Keywords
cesarean section, postoperative pain, Diclofenac suppository, Diclofenac intramuscular
Brief summary
The goal of this clinical study is to find out which way of giving diclofenac sodium provides better pain relief after a planned cesarean section: an injection into the muscle or a suppository given through the rectum. Diclofenac is a commonly used pain-relieving medicine after surgery. Women often experience moderate pain after a cesarean section, and effective pain control helps with early movement, breastfeeding, and overall recovery. Different methods of giving the same medicine may work differently and may affect how comfortable patients feel after surgery. This study compares these two methods to see which one reduces pain more effectively. Researchers will compare post-operative pain levels in women who receive intramuscular diclofenac with those who receive rectal diclofenac after elective cesarean section. The main questions this study aims to answer are: * Does intramuscular diclofenac provide better pain relief than rectal diclofenac after cesarean section? * Is there a difference in the need for additional (rescue) pain medicine between the two groups? Participants will be women aged 20 to 45 years who are undergoing a planned cesarean section at term. A total of 60 women will take part in the study. They will be randomly assigned to one of two groups: * One group will receive diclofenac as an intramuscular injection every 8 hours for the first 24 hours after surgery. * The other group will receive diclofenac as a rectal suppository every 8 hours for the same period. All participants will receive standard spinal anesthesia for surgery. Pain will be measured using a simple pain scale at 1, 6, 12, and 24 hours after the operation. If a participant reports significant pain, additional pain medicine will be given. The results of this study will help doctors choose the most effective and comfortable method of pain relief for women after cesarean section.
Interventions
DRUGDiclofenac 75mg
Participants will be given intramuscular diclofenac 75mg 8hourly for first 24-hours after cesarean section
DRUGDiclofenac 50mg
Participants will be given diclofenac suppository every 8 hours for first 24-hours after cesarean section
Sponsors
CMH Multan Institute of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* 37 - 42 weeks of gestation * planned to go for elective cesarean section
Exclusion criteria
* Women already on long-term analgesics * known hypersensitivity to any of the study medications * known diabetics (chronic or GDM)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain | Pain will be assessed at 1, 6, 12 and 24-hours after cesarean section | Pain will be assessed on visual analog scale by the blinded assessor |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rescue Analgesia | From cesarean section to 24-hours postoperatively | In cases of VAS \> 4, extra analgesia (rescue analgesia) will be given to control pain |
Countries
Pakistan
Contacts
STUDY_CHAIRNidda Y Assistant Professor, FCPS
CMH Multan Institute of Medical Sciences
Outcome results
None listed