Nausea, Pregnancy Emesis
Conditions
Brief summary
This is a prospective, two-arm, non-blinded randomized controlled study designed to evaluate the effects of a one-week alternate nostril breathing (ANB) intervention on nausea and vomiting severity in pregnant individuals during their first trimester.
Interventions
BEHAVIORALAlternate Nostril Breathing
ANB 3 times per day for 5-10 minutes per session over a 7-day period
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Pregnant individuals aged 18 years or older * Viable pregnancy with a gestational age between 6 0/7 - 12 6/7 weeks of gestation, confirmed by last menstrual period or ultrasound * Diagnosed with mild to moderate NVP (PUQE-24 score between 4-12) * Ability to understand and read English
Exclusion criteria
* Severe nausea and vomiting, defined as a PUQE score \>12, or diagnosis of hyperemesis gravidarum requiring hospitalization or intravenous fluid therapy * Pre-existing, active or acute respiratory conditions (e.g., asthma, COPD) * History of severe anxiety disorders affecting breathing patterns * Known deviated nasal septum * Nausea and vomiting that pre-dates the pregnancy or is suspected to be due to a etiology other than pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Severity of Nausea and Vomiting | Day 7 | Measured by the change in the Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) score, where scores range from 3-15, and a higher score indicates greater severity of nausea and vomiting. |
Countries
United States
Contacts
CONTACTErin Wesley
PRINCIPAL_INVESTIGATORShilpa Babbar
University of Minnesota
Outcome results
None listed