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Social COgnition Screening

Evaluation of Social Cognition: A New Screening Approach for Autism

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07377227
Acronym
ECoS-A
Enrollment
128
Registered
2026-01-29
Start date
2026-02-01
Completion date
2028-12-01
Last updated
2026-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye-tracking, Autism Spectrum Disorder, Social Cognition, Diagnosis

Keywords

Eye-tracking, Autism Spectrum Disorder, Social Cognition, Diagnosis

Brief summary

Social cognition refers to the mental processes involved in social interactions, including social perception, motivation, communication, emotion recognition, and theory of mind. Face perception plays a key role in children's social development, but children with Autism Spectrum Disorder (ASD) tend to look less at social stimuli, especially faces, than typically developing (TD) peers. Eye-tracking studies highlight these visual exploration differences, linked to difficulties in joint attention, emotion recognition, and theory of mind, as well as in executive and memory functions. Standard diagnostic tests often require active participation and sufficient language, which makes assessment challenging for children with ASD and additional cognitive or language impairments. This research project investigates how visual activity supports social cognition depending on cognitive and language levels, hypothesizing that eye-tracking can provide useful indicators for ASD screening and diagnosis.

Interventions

eye-tracking

cognitive assessments

Sponsors

Centre Hospitalier Universitaire, Amiens
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
4 Years to 10 Years
Healthy volunteers
Yes

Inclusion criteria

* ASD Group: * Boys or girls diagnosed with Autism Spectrum Disorder (based on clinical tools and observations) * Aged between 4 and 10 years old * Affiliation with a social security scheme * Informed consent of those with parental authority * DT Group: * Boys or girls * Aged between 4 and 10 * Attending school in the Hauts-de-France region * Affiliation with a social security scheme * Consent of those with parental authority

Exclusion criteria

* For ASD: Uncorrected visual or auditory impairments. * For DT: Intellectual disability, neurological or genetic disorders, autistic traits reported by teachers. The discrepancy between actual age and abilities calculated on the basis of standardised test scores

Design outcomes

Primary

MeasureTime frameDescription
differences in visual exploration patterns between both groups2 yearsDifferences in visual exploration patterns between both groups Visual exploration patterns are determined with TOM Test Battery, PPVT-5, Raven's 2 and FEE tests
Classification performance of machine learning algorithms in distinguishing ASD from TD2 yearsClassification performance of machine learning algorithms in distinguishing ASD from TD

Secondary

MeasureTime frameDescription
Identification of cognitive subgroups within ASD group2 years
Correlations between eye-tracking measures and cognitive scores2 yearsEye-tracking patterns are determined with TOM Test Battery, PPVT-5, Raven's 2 and FEE tests
Developmental trajectory analysis in TD children2 years

Countries

France

Contacts

CONTACTFederica Cilia, MD
Cilia.Federica-ext@chu-amiens.fr33+3 22 66 75 40

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026