Crohn's Disease, IBD, Pregnancy, Ulcerative Colitis
Conditions
Keywords
IBD, Crohn's disease, Ulcerative colitis, pregnancy
Brief summary
Inflammatory Bowel disease, including Crohn's disease and Ulcerative Colitis, are chronic diseases. Diagnosis is most often done in women of childbearing age. IBD can have and increase the risk of intrauterine growth retardation, preterm birth… Conversely, pregnancy can have an impact on IBD activity during pregnancy. Moreover, IBD course can be influence in post-partum. The investigators will explore IBD course on 945 patients from the EPIMAD register. The investigators will cross the data on the IBD with data on pregnancy, postpartum but also breastfeeding. The principal aim of this study is to assess the number of flares during pregnancy.
Interventions
None listed
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* women between 18 and 50 years old * MICI diagnosed between 1988 and 2018 * included in EPIMAD registry * living in Somme * having had at least one pregnancy
Exclusion criteria
* women who has not had pregnancy * not included in EPIMAD register
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of IBD flare during pregnancy | 2 years |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number and indication of cesarean section | 2 years | — |
| Number of anoperineal lesions after the birth | 2 years | — |
| Wexner score for continence | 2 years | — |
| Number of women with exposition to corticosteroid | 2 years | Exposition to corticosteroid during pregnancy and post-partum |
| Number of flare during post-partum period | 2 years | — |
| Number of pregnancy | 2 years | — |
| number of children | 2 years | — |
| Number of Intestinal resection | 2 years | Intestinal resection due to mici during pregnancy and post-partum |
| Number of hospitalization | 2 years | Intestinal resection and hospitalization due to mici during pregnancy and post-partum |
| Number of miscarriage | 2 years | — |
| Number of ectopic pregnancy | 2 years | — |
| Exposition to biotherapy | 2 years | Exposition to biotherapy during pregnancy and post-partum |
| Time before conception | 2 years | — |
Countries
France
Contacts
CONTACTArthur FOULON, Pr
Outcome results
None listed