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Acute Effect of Graded Motor Imagery on Ankle Rehabilitation: A Pilot Study

The Acute Effect of Graded Motor Imagery-Based Mental Preparation on Ankle Rehabilitation: A Pilot Clinical Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07376915
Enrollment
48
Registered
2026-01-29
Start date
2026-02-09
Completion date
2026-06-09
Last updated
2026-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankle Instability, Healthy Controls

Brief summary

The primary aim of this study is to evaluate the immediate and short-term effects of the Graded Motor Imagery (GMI) method on individuals with chronic ankle instability (CAI). In this context, the effects of the Graded Motor Imagery intervention on pain level, muscle stiffness, muscle strength, functional performance, and subjective instability level will be investigated. Additionally, these effects will be comparatively analyzed with an age- and sex-matched control group consisting of healthy individuals.

Interventions

The Graded Motor Imagery (GMI) program will be applied six consecutive days nd will consist of three progressive stages: Laterality Training: Participants will perform right-left ankle discrimination tasks using validated foot and ankle images. Accuracy and response time will be recorded. Motor Imagery: Participants will mentally rehearse ankle movements such as dorsiflexion, plantarflexion, inversion, and eversion without performing the motion. Imagery tasks will progress from simple movements to functional patterns based on tolerance. Mirror Therapy: A mirror will be placed in the midsagittal plane, allowing participants to view the reflection of the non-affected ankle while performing movements. The visual illusion of normal movement is intended to improve motor control and proprioception.

Sponsors

Istanbul University - Cerrahpasa
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Aged between 18 and 40 years. * Diagnosed with chronic ankle instability (CAIT ≤ 24). * History of an acute ankle sprain occurring more than 3 months prior to enrollment. * Has not received ankle rehabilitation treatment. * Voluntarily participated in this study

Exclusion criteria

* Vestibular or neurological disorders * Other lower extremity injuries * History of surgery

Design outcomes

Primary

MeasureTime frameDescription
Subjective Instability (CAIT)baselineA valid-reliable questionnaire that questions the perceived instability in daily life and sports activities. Clinical Significance: ≥ 3 point increase is considered clinically significant
Ground Reaction Force & Static Balance (ForceDecks)baselineDevice: ForceDecks dual force platform. 1. Single-Leg Jump Test\* Values: Net vertical ground reaction force (N·kg-¹), flight time (ms), asymmetry (%). 2. Single-Leg Static Balance\* Values: Total sway path (mm), ellipse area (mm²). Clinical Importance:\* Captures short-term changes in neuromuscular control and explosive strength in a detailed manner.

Secondary

MeasureTime frameDescription
Muscle Stiffness (Myoton PRO)baselineTonic stiffness (N·m-¹) reflects the passive mechanical properties of muscle tissue. The device applies a 0.4 N mechanical impulse to the skin and records the resulting tissue oscillation response. In this study, data will be recorded as the average of 3 impulses. Clinical Importance: Acute changes in stiffness are considered an indirect indicator of neuroplastic responses in proprioception and motor control.
Muscle Strength Assessment - Isokinetic dynamometer (Isoforce)baselineParameter: Concentric inversion-eversion peak torque (Nm) at 60°·s-¹ Objectively measures agonist-antagonist muscle performance around the ankle joint. Clinical Significance:\* Improvements in strength contribute to functional stability and a reduced risk of re-injury.
Pain LevelbaselineVisual Analog Scale (VAS, 0-10 cm): 0 = "no pain," 10 = "unbearable pain"; the participant marks the scale before and after the session.
Functional PerformancebaselineStar Excursion Balance Test (SEBT) Parameter: Normalized reach distance in three primary directions (anteromedial, medial, posteromedial), expressed as a percentage of leg length. Clinical Significance: Assesses dynamic balance and lateral load-transfer capacity; asymmetries in individuals with chronic ankle instability (CAI) may serve as prognostic indicators.

Countries

Turkey (Türkiye)

Contacts

CONTACTSEDA ATEŞ, Bachelor degree
seda.ates@ogr.iuc.edu.tr90+ 5388543087
STUDY_DIRECTORSEZEN KARABÖRKLÜ ARGUT, Assistant Professor, PhD

Istanbul University-Cerrahpaşa, Faculty of Health Sciences

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 12, 2026