Congenital Heart Disease (CHD)
Conditions
Keywords
Smartphone, Mobile Applications, Telemedicine, Heart Defects, Congenital, Phonocardiography, Heart Sounds, Heart Murmurs, Heart Auscultation
Brief summary
This observational study aims to assess the performance of the software called ausculto™. ausculto™ is a collection of computer algorithms that intend to analyse heart sounds recorded from the built-in microphone of a smartphone for abnormal sounds. Participants will have their heart sounds recorded during their normal attendance at the hospitals after consenting to participate in this study. Researchers will manually annotate the recorded heart sounds to create a database for use in future training and testing of artificial intelligence (AI) intended for medical uses.
Interventions
DIAGNOSTIC_TESTComputer algorithms
Collection of lightweight computer algorithms called ausculto™ that is designed to perform real-time heart sound analysis to detect heart murmur.
Sponsors
The University of Hong Kong
Laboratory of Data Discovery for Health
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
6 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age: ≥ 6 years * Have undergone echocardiography within 3 years at their normal non-research hospital attendance
Exclusion criteria
* Implanted active medical devices in the torso, such as pacemakers and defibrillators * Have purely non-congenital valvular heart disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Differentiation of Murmurs Associated with Congenital Heart Disease from Normal Heart Sounds and Innocent Murmurs in Heart Sound Recordings | Day 0 | Identification of murmurs associated with congenital heart disease from normal heart sounds and innocent murmurs in recorded heart sounds (phonocardiogram \[PCG\]), measured in the form of sensitivity and specificity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Differentiation of Murmurs Associated with Congenital Heart Disease from Normal Heart Sounds and Innocent Murmurs in Heart Sound Recordings | Day 0 | Identification of murmurs associated with congenital heart disease from normal heart sounds and innocent murmurs in recorded heart sounds (phonocardiogram \[PCG\]), measured in the form of positive and negative predictive value and accuracy. |
| Number of Adverse Events Reported by Participants or Child Participants' Parent/Legal Guardian During and at the End of Heart Sound Recording That are Determined to be Caused by This Study | Day 0 | — |
Countries
Hong Kong
Outcome results
None listed