The Role of Inflammatory Biomarkers in Preventing Deep Sternal Wound Infections After Sternotomy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07376070

Enrollment

Registered

2026-01-29

Start date

2025-04-14

Completion date

2028-04-14

Last updated

2026-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep Sternal Infection, Diabete Mellitus, Mediastinitis

Brief summary

The goal of this observational study is to reveal blood biomarkers that will have prognostic significance in terms of the development of deep wound infection following sternotomy. As for the practical significance of the study, blood biomarkers correlated with deep wound infections can be used to prevent the development of wound infections in the postoperative period. Based on this, it is possible to formulate an algorithm for preventive measures.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* deep sternal wound infection

Exclusion criteria

* bilateral internal thoracic artery graft

Design outcomes

Primary

Measure	Time frame
change in pre and postoperative inflammatory biomarker levels associated with development of deep sternal wound infection within 1 month	within 30 days after surgery

Countries

Georgia

Outcome results