Choroid
Conditions
Brief summary
This study aims to bridge that gap by investigating how acute sugar intake influences choroidal thickness.
Detailed description
This investigation will be a prospective, repeated-measures study. All subjects will arrive fasted and will be asked not to consume any outside food or beverages during the three-hour study period, and will be asked to abstain from caffeine intake for 12 hours before participation. A baseline OCT scan of the macula of the right eye will be performed using the Heidelberg Spectralis OCT system. Participants will then consume 30 grams of sugar in the form of glucose tablets. Macular OCT scans of the right eye will be repeated every 30 minutes for 3 hours following sugar consumption.
Interventions
DIETARY_SUPPLEMENTOral glucose
Participants will consume 30 grams of sugar in the form of glucose tablets.
Sponsors
Southern College of Optometry
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* In order to be eligible for enrolment, each subject must have less than 6 diopters of spherical equivalent refractive error, and have no existing diagnosis of diabetes or pre-diabetes.
Exclusion criteria
* Any potential subject with known retinal pathology will be excluded. Any potential subject with any other known systemic or ocular conditions that may impact their ability to participate in the study or provide generalizable data will also be excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in choroidal thickness | within 3 hours of baseline | The primary outcome for this investigation will be changes in choroidal thickness from baseline across timepoints. |
Countries
United States
Contacts
CONTACTMorgan Ollinger, OD, MS
Outcome results
None listed