Glioblastoma (GBM)
Conditions
Keywords
newly diagnosed, Glioblastoma, Music Therapy
Brief summary
The Brain Cancer Program, in partnership with the Center for Music and Medicine at Johns Hopkins, will study whether music therapy is feasible in newly diagnosed GBM patients undergoing standard care.
Detailed description
Virtually via Zoom, all participants will meet with Music Therapists to create playlists and learn how to complete surveys measuring quality of life. Participants will be randomly assigned, half to each arm. Arm A will interact with Music Therapists and listen to music twice a week, then independently fill out quality of life questionnaires. Arm B will listen to music independently twice a week, then independently fill out quality of life questionnaires.
Interventions
OTHERMusic intervention
Each GBM study participant in Arm A will receive two 30-minute live synchronous virtual music therapy sessions per week for a period of 8 weeks to be curated by a board-certified music therapist. Arm B participants will receive curated playlists of music created by a music therapist. Participants will then listen to the curated music playlists on the participant's own device twice per week. All participants will complete a total of 16 music therapy sessions, scheduled twice per week over 8 weeks. Each session will last approximately 30 minutes.
Sponsors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Keep Punching Foundation
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
This study will assess the feasibility of Music Therapy in the high-risk, high-needs population of individuals newly diagnosed with GBM and undergoing standard of care adjuvant chemotherapy.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Glioblastoma (Newly Diagnosed) * Cognitive capacity to respond to surveys * Access to computer and web access * Ability to attend virtual music therapy sessions * Audibly process music * Proficient in English
Exclusion criteria
* Not planning to undergo standard of care radiation therapy and concurrent and adjuvant temozolomide. * A life expectancy of less than 6 months. * Concurrent use of any other standard or investigational agents (excepting tumor treating fields). * Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection or psychiatric illness/social situations that would limit adherence with study requirements.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Success rate of Music Therapy intervention for GBM patients | 6 months | Determine success rate of the delivery of individualized virtual music therapy (MT) in participants undergoing standard of care treatment for newly diagnosed glioblastoma. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rate of survey completion | 2 years | Rate of participants completing all surveys. |
Countries
United States
Contacts
CONTACTPrincipal Investigator- Matthias Holdhoff, MD, PhD.
PRINCIPAL_INVESTIGATORMatthias Holdhoff, MD, PhD.
Johns Hopkins -Sidney Kimmel Cancer Center
PRINCIPAL_INVESTIGATORGrace Tobin, MD
Johns Hopkins University
Outcome results
None listed