Hypercholesterolemia
Conditions
Brief summary
Evaluation of adherence, persistence, and efficacy of treatment with Bempedoic acid in a real-life Italian population.
Interventions
DRUGBempedoic acid
film-coated tablets
Sponsors
Federico II University
Study design
Observational model
CASE_ONLY
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients under Bempedoic acid treatment
Exclusion criteria
* Age \< 18 years o \> 80 years * Patients who refuse to participate and to sign informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Description of adherence to treatment with Bempedoic acid in a real-life Italian population | 6-12-24-36 months | Adherence will be assessed in terms of Medical Possession Ratio (MPR), which is defined as the ratio between the treatment units dispensed during the treatment period and the duration of the treatment period itself. |
| Description of efficacy of treatment with Bempedoic acid in a real-life Italian population | 6-12-24-36 months | Efficacy of treatment will be evaluated as a change in the LDL (deltaLDL) value from the start of treatment (percentage and absolute value). |
| Description of persistence to treatment with Bempedoic acid in a real-life Italian population | 6-12-24-36 months | Persistence will be assessed in terms of therapeutic continuity from the start of treatment to enrollment. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Description of safety of treatment with Bempedoic acid in a real-life Italian population | 6-12-24-36 months | Safety will be evaluated in terms of adverse reactions or intolerance to the drug. |
Countries
Italy
Contacts
CONTACTPasquale Perrone Filardi
Outcome results
None listed