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Modified vs. Conventional Laparoscopic TAPP for Inguinal Hernia

A Randomized Controlled Trial Comparing Modified Tumescent vs. Conventional Laparoscopic TAPP for Inguinal Hernia Repair

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07373314
Enrollment
60
Registered
2026-01-28
Start date
2026-02-10
Completion date
2026-08-30
Last updated
2026-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inguinal Hernia Repair

Brief summary

This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP). The primary goal is to determine which technique provides better outcomes in terms of operative time, ease of pre-peritoneal space dissection, postoperative pain, and the formation of seromas. The study will involve 60 patients diagnosed with unilateral inguinal hernias, randomly assigned to either group. Participants in Group A will undergo the MT-TAPP procedure, which involves pre-peritoneal infiltration of a local anesthetic solution to improve dissection and reduce pain. Group B will undergo the standard CL-TAPP procedure. Data will be collected on various outcome measures and analyzed to identify which technique leads to quicker recovery, less postoperative pain, and fewer complications. The results of this study will help guide surgical decisions and improve patient outcomes in inguinal hernia repair.

Interventions

OTHERModified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group.

In this intervention, participants will undergo laparoscopic inguinal hernia repair using the modified tumescent technique. This technique involves pre-peritoneal infiltration of a solution containing lidocaine, epinephrine, and saline. The tumescent solution is injected into the peritoneum to create a "tumescent" effect, making the tissues easier to dissect and reducing bleeding. This approach aims to improve surgical visibility, reduce operative time, minimize postoperative pain, and shorten the learning curve for less experienced surgeons. The rest of the procedure follows the standard laparoscopic TAPP repair, with mesh placement and peritoneal closure.

OTHERConventional Laparoscopic TAPP (CL-TAPP)

In this intervention, participants will undergo the conventional laparoscopic transabdominal preperitoneal (TAPP) hernia repair. This standard technique involves placing three ports to access the inguinal region, followed by dissection of the pre-peritoneal space and placement of a mesh to repair the hernia. The conventional method does not use tumescent infiltration and relies solely on the surgeon's skill to navigate the anatomical structures. This approach is well-established and commonly used in inguinal hernia repairs, but it may be associated with longer operative times and more postoperative pain compared to the modified technique.

Sponsors

University of Health Sciences Lahore
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* Age: 18 to 50 years. * Gender: Both male and female participants. * Condition: Diagnosed with unilateral inguinal hernia (as per operational definition). * Health Status: ASA I-III (American Society of Anesthesiologists physical status classification), indicating that the patient is fit for surgery. * Consent: Participants must be able to provide informed consent to participate in the study.

Exclusion criteria

* Femoral Hernias. * Incarcerated or Strangulated Hernia. * Recurrent Hernias (as per medical record). * Serious Systemic Diseases: * Conditions such as heart failure or coagulation problems (e.g., PT \> 15 sec). * ASA III-V classification, indicating a higher risk for surgery. * Pregnancy (if applicable). * Allergy to Anesthesia or the substances used in the tumescent solution (lidocaine, epinephrine, saline). * Uncontrolled Diabetes or other medical conditions that might interfere with the healing process.

Design outcomes

Primary

MeasureTime frameDescription
Pain ScoreRecorded 24 hours post-surgery.A score of 0 represents no pain, while a score of 10 represents the worst pain.
Seroma Formation:Presence or absence of seroma, assessed during the 7-day postoperative follow-up.

Contacts

CONTACTDr. Taseen Imran
taseenimran5@gmail.com923045079008

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026