Mechanomyography, Neuromuscular Blockade Monitoring
Conditions
Keywords
mechanomyography, tetanic fade
Brief summary
In clinical anesthesiologic practice, most institutions use acceleromyography in order to assess the degree of a neuromuscular block. The aim of the present study is to assess a new device using mechanomyography. Until recently, this method was reserved for experimental settings. It seems to be able to work more precisely, and additionally, it offers the opportunity to use other stimulation patterns than acceleromyographic measurements. The investigation is divided into two parts: Part 1 compares the mechanomyograph directly with an acceleromyograph. In part 2, two mechanomyographs using different stimulation patterns are compared with each other.
Interventions
DEVICEmeasurement of the time course of a neuromuscular block
a new device is compared to an established one.
Sponsors
Klinikum Hersfeld-Rotenburg
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* patients scheduled for surgery requiring general anesthesia with neuromuscular blocking agents
Exclusion criteria
* anticipated or known difficult airway * increased risk for aspiration * pregnancy * neuromuscular disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| difference in time to recovery to a train of four ratio of 1,0. | from enrollment to the end of anesthesiologic treatment at the day of surgery (2-3 weeks after enrollment) | difference in time to recovery to a train of four ratio of 1,0 measured by acceleromyography and mechanomyography, respectively |
Countries
Germany
Contacts
CONTACTStefan Soltesz, Professor
Outcome results
None listed