ICU Admission Diagnoses and ICU Mortality

Association of Admission Syndromic Diagnoses With ICU Mortality in a Mixed Adult Intensive Care Unit: Retrospective Cohort

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07369206

Enrollment

1248

Registered

2026-01-27

Start date

2026-01-30

Completion date

2026-02-02

Last updated

2026-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome (ARDS), Acute Respiratory Failure, Critical Illness, Multiple Organ Dysfunction Syndrome, Sepsis, Septic Shock

Keywords

Intensive Care Unit, ICU Mortality, Admission Diagnosis, Retrospective Cohort, Severity Score, APACHE II, SAPS, SOFA, Length of Stay

Brief summary

This retrospective cohort study will evaluate whether syndromic clinical diagnoses present at ICU admission are associated with ICU mortality, independent of physiologic severity scores. Adult patients admitted to a tertiary mixed ICU during 2025 will be assessed.

Detailed description

Data will be obtained retrospectively from the hospital information system and ICU clinical records. Variables will be recorded based on the first 24 hours after ICU admission. Demographics, admission characteristics, comorbidities, severity scores (APACHE II, SAPS, SOFA), and admission syndromic diagnoses (e.g., sepsis/septic shock, acute respiratory failure, ARDS, MODS) will be collected. The primary outcome is ICU mortality; secondary outcomes include ICU length of stay and ICU discharge disposition.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patients (≥18 years) admitted to the ICU between January 1, 2025 and December 31, 2025. * If a patient has more than one ICU admission during the study period, only the first ICU admission will be included.

Exclusion criteria

* ICU stay \<24 hours. * Missing essential data preventing assessment of the primary outcome (ICU mortality) and/or calculation of severity scores (APACHE II, SAPS, SOFA).

Design outcomes

Primary

Measure	Time frame	Description
ICU mortality	From ICU admission until ICU discharge (end of index ICU stay), assessed up to 90 days	Death occurring during the index ICU stay (ICU mortality), abstracted from electronic medical records.

Secondary

Measure	Time frame	Description
ICU length of stay (LOS)	From ICU admission to ICU discharge (index ICU stay), assessed at ICU discharge (up to 90 days)	ICU length of stay (days) during the index ICU admission, calculated as the difference between ICU admission and ICU discharge timestamps in the electronic medical record.
ICU discharge disposition	At ICU discharge (index ICU stay; assessed at the time of ICU discharge in the medical record, up to 90 days)	Disposition at ICU discharge categorized as: death in ICU, transfer to hospital ward, or transfer to another facility; determined from the ICU discharge documentation in the electronic medical record.

Countries

Turkey (Türkiye)

Outcome results