TKA Outcomes
Conditions
Keywords
TKA, iKA, aMA
Brief summary
General Aim: to explore the iKA in TKA related to clinical, biomechanical, and functional outcomes.
Detailed description
First specific aim: to investigate the kinematics during daily functional movements in individuals with the iKA TKA to those with aMA TKA, as well as the healthy control group. Second specific aim: to investigate kinetics and muscle activation patterns during functional movements in individuals with the iKA aligned TKA to those with aMA TKA, as well as a healthy control group. Third specific aim: to investigate the impact of the whole body on functional outcomes following iKA and aMA TKA, in comparison to the healthy control group, and to explore the underlying factors contributing to suboptimal outcomes.
Interventions
PROCEDUREiKA
This study compared inverse kinematic alignment (iKA) TKA, which preserves native JLO, with adjusted mechanical alignment (aMA) TKA, which standardizes JLO to 90°, and a healthy control group across eight functional activities.
Sponsors
KU Leuven
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
55 Years to 85 Years
Healthy volunteers
Yes
Inclusion criteria
were age under 85 years. primary robot-assisted TKA using either iKA or aMA. surgery performed two years before enrollment. independent ambulation without assistive devices; and informed consent.
Exclusion criteria
history of lower limb trauma or fracture. neurological disorders (e.g., stroke, Parkinson's disease, multiple sclerosis). systemic musculoskeletal diseases (e.g., rheumatoid arthritis, diabetic neuropathy). revision arthroplasty. and cognitive impairment affecting study participation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hand Thickness | 2 years after TKA | Vernier caliper, Hand Thickness in millimeters |
| Visual Analog Scale | Pre-TKA, 6 weeks after TKA, 2 years after TKA | Pain Scores |
| Oxford Knee Score (OKS) | Pre-TKA; 2 years after TKA | total score ranging from 0 to 48 |
| Total Gait Cycle Duration | 2 years after TKA | Vicon Nexus 2.12 software (©Vicon Motion Systems Ltd., Oxford, UK); Unit in second |
| maximum voluntary isometric strength tests of the lower limb | 2 years after TKA | Peak force measured with a hand-held dynamometer (Micro FET 2 Handheld Dynamometer, Hoggan, USA); Unit: Newtons |
| Muscle activity patterns for eight muscles (gluteus medius, rectus femoris, vastus medialis, vastus lateralis, biceps femoris, semitendinosus, tibialis anterior and gastrocnemius medialis) | 2 years after TKA | A 16-channel telemetric wireless surface electromyography (EMG) system (Waveplus®, Cometa, Rome, Italy) operating at 1000 Hz was utilized. Unit: Volt |
| Height | 2 years after TKA | Stadiometer; height in millimeters |
| Joint angles | 2 years after surgery | Vicon Nexus 2.12 software (©Vicon Motion Systems Ltd., Oxford, UK); Unit: Degrees |
| Age | 2 years after TKA | year |
| Leg Length | 2 years after TKA | Direct Tape Measure; Leg Length in millimeters |
| Inter-ASIS Dist | 2 years after TKA | Vernier caliper， Inter-ASIS Dist in millimeters |
| Knee Width | 2 years after TKA | Vernier caliper, Knee Width in millimeters |
| Ankle Width | 2 years after TKA | Vernier caliper, Ankle Width in millimeters |
| Elbow Width | 2 years after TKA | Vernier caliper, Elbow Width in millimeters |
| Wrist Width | 2 years after TKA | Vernier caliper, Wrist Width in millimeters |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| BMI | 2 years after TKA | weight and height will be combined to report BMI in kg/m2 |
Countries
Belgium
Outcome results
None listed