Dry Eye, Obesity, Polycystic Ovary Syndrome
Conditions
Brief summary
Women with polycystic ovarian syndrome (PCOS) may complain dryness of their eyes especially obese ones. lifestye changes are main treatrment fro both problems
Detailed description
Forty females with PCOS, eye dryness , and obesity will asigned to group I or Group II, n=20 for each group. Both groups will receive metformin thrice times daily and low calorie diet for 12 weeks. Group I, additionally will perform one hour of treadmill walking thrice weekly for 12 weeks.
Interventions
BEHAVIORALexercise and limiting diet
twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks. Group I, additionally will perform one hour of treadmill walking thrice weekly for 12 weeks.
BEHAVIORALdiet limitation
twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* PCOS women * obese class I * bilateral dryness of eye
Exclusion criteria
* liver disoease * cardiac disease * renal disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| schrimer test | it will be measured after 12 weeks | it is a test for assessment dye dryness |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Ocular surface disability index | It will be measured after 12 weeks | it is a questionaire for assessment dye dryness |
| dry eye scoring system | It will be measured after 12 weeks | it is a questionaire for assessment dye dryness |
| Tear film break-up time | It will be measured after 12 weeks | it is a test for assessment dye dryness |
| body mass index | it will be measured after 12 weeks | it will be assessed on empty stomach and bowel |
| wasit hip ratio | It will be measured after 12 weeks | it will be assessed by dividing wasit circuference on hip circumference |
| wasit circumference | It will be measured after 12 weeks | it will be assessed by tape measure |
| testesterone | It will be measured after 12 weeks | it will be assessed in serum |
| LH:FSH ratio | It will be measured after 12 weeks | The LH (Luteinizing Hormone) to FSH (Follicle-Stimulating Hormone) ratio shows the balance between these reproductive hormones |
| dehydroepiandrosterone | It will be measured after 12 weeks | it will ne assessed in serum |
Countries
Egypt
Contacts
CONTACTAli MA Ismail, lecturer
CONTACTAli Ismail
PRINCIPAL_INVESTIGATORAli MA Ismail, lecturer
Cairo University
Outcome results
None listed