Insulin Resistance-abdominal Fats -Post Menopausal Women
Conditions
Brief summary
The aim of the study is to determine the effect Dry Needling of on insulin resistance in obese postmenopausal women.
Detailed description
Insulin resistance and abdominal obesity have a negative impact on quality of life of postmenopausal women. Obesity and, more specifically, the level of intra-abdominal fat, are positively associated with cardiovascular disease and cardiovascular disease risk factors such as increased plasma lipids and lipoproteins, hyperinsulinemia, and insulin resistance. This study has shown associations among menopause, body fat, and body fat distribution, suggesting that increased abdominal fat distribution could partially mediate the increased cardiovascular disease risk of postmenopausal women . Abdominal obesity can reflect excess of visceral fat tissue or subcutaneous or both. Visceral fat contributes to the pathogenesis of glucose intolerance and insulin resistance. Insulin resistance is an impaired condition of glucose absorption that induced by insulin .It represents a significant medical and socioeconomic issue impacting women's health and quality of life. So there is clinical experience and documentation for the effectiveness of Dry Needling in the treatment of insulin resistance in obese post-menopausal women.
Interventions
OTHERDry Needle
Dry Needle has been used to treat obesity. Clinical research has found that it is particularly effective for abdominal fat loss.Dry needling in the abdominal region requires an in-depth understanding of the underlying anatomy due to significant safety risks.
OTHERabdominal exercises, and medical standard care for insulin resistance
To reduce belly fat, combine core-strengthening exercises like planks, bicycle crunches, and leg raises with overall fat-burning cardio (walking, running) and a healthy diet
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
48 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* • All participants post-menopausal from at least 3 years. * All participants' ages will be ranged from 48-60 years old. * All participants BMI will exceed 25-30 kg/m2. * All participants waist hip ratio will be equal or more than 0, 90.
Exclusion criteria
* • Surgical liposuction within the last 12 months. * Untreated hypo- or hyperthyroidism. * Uncontrolled liver, kidney or cardiovascular disease or diabetes. * Implanted pacemaker or metal implant. * History of thrombophlebitis, any hematological disease. * No past or present neurological and musculoskeletal disorders that will have affected health condition. * No smoking and drinking habits. * No psychological problems.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HOMA-IR | 4 months | Outcome measures, HOMA-IR (Homeostasis Model Assessment) will be used to assess insulin resistance. HOMA-IR is a model of interactions between glucose and insulin dynamics that is then used to predict fasting steady-state glucose and insulin concentrations for a wide range of possible combinations of insulin resistance and β-cell function. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| ultrasound | 4 months | Abdominal fat thickness will be assessed by ultrasound (Aplio 500-model TUS-A500, fundamentals (2B77-004EN\*M) |
| BMI by kg/m2 | 4 months | weight and height will be combined to report BMI in kg/m\^2 |
| waist circumferences by tape | 4 months | — |
| The surface under the cumulative ranking curve (SUCRA) | 4 months | The surface under the cumulative ranking curve (SUCRA) was used to rank and compare the effects of different types of exercise. SUCRA values range from 0 to 100, where 100 indicates the best treatment with no uncertainty and 0 indicates the worst treatment with no uncertainty. Thus, higher SUCRA values indicated the better effects of an exercise intervention prior to and after four-month treatment duration for both groups. |
Countries
Egypt
Contacts
PRINCIPAL_INVESTIGATORShymaa Mohammed
out patient clinic ,faculty of physical therapy ,Cairo university ,Cairo,Egypt
Outcome results
None listed