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Testing Alcohol Cancer Risk Messages

Developing and Testing AI-Generated Messages on Alcohol and Cancer Risk: A Proof of Concept

Status
Enrolling by invitation
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07365813
Enrollment
850
Registered
2026-01-26
Start date
2026-04-21
Completion date
2028-03-30
Last updated
2026-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol, Cancer

Keywords

alcohol, alcohol warning labels, cancer survivors

Brief summary

Testing gain vs loss-framed messages to address drinking among cancer survivors

Interventions

BEHAVIORALText-only messages

The study will test eight alcohol-cancer risk messages (four gain-framed and four loss-framed). Each message will be developed at three intensity levels (text-only, neutral image, and graphic image), yielding 24 total message stimuli.

BEHAVIORALAI-developed Neutral pictorial messages

The study will test eight alcohol-cancer risk messages (four gain-framed and four loss-framed). Each message will be developed at three intensity levels (text-only, neutral image, and graphic image), yielding 24 total message stimuli.

BEHAVIORALAI-developed graphic pictorial messages

The study will test eight alcohol-cancer risk messages (four gain-framed and four loss-framed). Each message will be developed at three intensity levels (text-only, neutral image, and graphic image), yielding 24 total message stimuli.

Sponsors

University of Miami
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age 21 years or older * Resident of the United States * Able to read and speak English * Diagnosed with one of the following cancers: mouth, throat, larynx, liver, colon, rectum, or breast * Current alcohol user (≥ 1 alcoholic drink in the past 30 days)

Exclusion criteria

* Adults unable to consent * Individuals younger than 21 * Not residing in the US * Non-alcohol users (\<1 drink) * Less than 50% completion of the survey

Design outcomes

Primary

MeasureTime frameDescription
Change in alcohol-cancer harm perceptionWithin 15 minutes on a single online session - from before message exposure (pre-exposure) to after message exposure (post-exposure).Change in participants' beliefs about experiencing cancer in the future due to alcohol use measured on a scale from 1 (not at all) to 5 (a lot). The outcome is the change on the mean score from the pre to post exposure.
Intention to Reduce Alcohol consumptionWithin 15 minutes on a single online session - from before message exposure (pre-exposure) to after message exposure (post-exposure).Change in participants' intention to reduce alcohol consumption in the next month, measured on a scale from 1 (not at all) to 5 (a lot). The outcome is the change on the mean score from the pre to post exposure.
Commitment to a limited drinking goal in the next monthWithin 15 minutes on a single online session - from before message exposure (pre-exposure) to after message exposure (post-exposure).Change in participants' intention to commit to a drinking limit goal in the next month, measured on a scale from 1 (not at all) to 5 (a lot). The outcome is the change on the mean score from the pre to post exposure.

Secondary

MeasureTime frameDescription
Message perceived effectivenessOne time (within 5 minutes) post-exposure evaluation.Self reported perceived overall effectiveness of the message measured on a scale from 1 (not at all) to 5 (a lot) scale. The outcome is the mean score.
Message ReceptivityOne time (within 5 minutes) post-exposure evaluation.Self reported message receptivity including attention, emotional reaction, believability, fear, relevance, anticipated social interactions, recall and avoidance on a scale from 1 (not at all) to 5 (a lot). The outcome is the composite mean score assessing attention, emotional reaction, believability, fear, relevance, anticipated social interactions, recall, avoidance, and perceived effectiveness. Higher scores indicate greater message receptivity.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORTaghrid Asfar, MD, MSPH

University of Miami

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 23, 2026