Colonoscopy, Colon Polyps
Conditions
Brief summary
The goal of this study is to use a colonoscope compatible device capable of taking images of the lower gastrointestinal tract. The main question it aims to answer is: Is the colonoscope compatible optical coherence tomography probe (CC-OCT probe) an effective device to use to take images of the gut? During the participant's standard of care colonoscopy, the CC-OCT probe will be inserted into the colonoscope. The CC-OCT probe will then collect images of the participant's gastrointestinal tract in real time.
Interventions
DEVICEFeasibility of using a CC-OCT probe to image the GI tract
250 participants will be enrolled in this study. All consented participants will receive the same intervention.
Sponsors
Massachusetts General Hospital
National Institutes of Health (NIH)
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
45 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* 45 years of age or older * Capable of giving informed consent * Capable of following bowel prep instructions
Exclusion criteria
* 75 years of age or older * Any contraindication to bowel prep or colonoscopy * Current diagnosis of any bleeding disorders * Currently using drugs that interfere with coagulation (excluding low-dose aspirin) * Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ability of the CC-OCT to image the lower GI tract | Images are collected during the study procedure and analyzed within one year of collection |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORGuillermo Tearney, M.D., PhD
Massachusetts General Hospital
Outcome results
None listed