Local Registry of Central Nervous System Infections (ReCeNSI)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07364539

Acronym

ReCeNSI

Enrollment

520

Registered

2026-01-23

Start date

2022-03-04

Completion date

2030-01-01

Last updated

2026-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Nervous System (CNS) Infection

Brief summary

Central Nervous System (CNS) infections are considered rare conditions but at the same time, they are emergencies whose diagnosis and treatment are time-dependent. They include several clinical syndromes, including meningitis, encephalitis, brain abscesses, and post-surgical meningitis. The classic triad of symptoms includes fever, altered mental status, and neck stiffness, but other common manifestations include nausea and vomiting, cranial nerve dysfunction, skin rash, and seizures. Due to the potentially life-threatening effects on patients, these clinical conditions cannot be underestimated. The CNS includes the brain and spinal cord, surrounded and protected by the meninges and cerebrospinal fluid (CSF). Within the CNS are numerous nuclei responsible for vital functions, as well as more complex intellectual activities.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Pazients admitted to the Fondazione IRCSS Policlinico San Matteo * Diagnosis of bacterial meningitis, meningoencephalitis, bacterial CNS infection, viral CNS infection, viral encephalitis, brain abscess, or post-neurosurgical meningitis.

Design outcomes

Primary

Measure	Time frame
To evaluate the outcome in terms of mortality at discharge in patients with CNS infections.	From January 2012

Countries

Italy

Outcome results