Rectal Carcinoma
Conditions
Brief summary
the study will discuss different pattern of treatment and the outcomes of locally advanced rectal carcinoma as a retrospective study. The study will be conducted at Department of Clinical Oncology, Sohag University Hospital and Sohag Cancer center, Sohag, Egypt. including patients diagnosed and treated between 2018 and 2025. and the data will be collected from reports .
Interventions
no intervention
Sponsors
Study design
Eligibility
Inclusion criteria
* patients who were more than18 years old at time of diagnosis. * Patients with histologically confirmed rectal carcinoma. * Stage II-III (locally advanced) disease at initial diagnosis.
Exclusion criteria
* Patients with distant metastasis at presentation. * Patients diagnosed with double malignancy. * Patients with incomplete medical records. * Organ failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimation of overall survival (OS ). | 2018 _ 2025 |
| Estimation of Response rate . | 2018-2025 |
| Estimation of disease-free survival (DFS) . | 2018-2025 |
Secondary
| Measure | Time frame |
|---|---|
| treatment-related toxicity: (graded by CTCAE v5). | 2018-2025 |