Gastric Cancer (GC), Obstructive Sleep Apnea
Conditions
Keywords
Radical gastrectomy, Severe obstructive sleep apnea
Brief summary
This study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
Detailed description
This study retrospectively included patients who underwent radical gastrectomycombined with severe obstructive sleep apnea at Qilu Hospital . Accordingto the assessment of anesthesiologists, whether the anesthetic drugs of the patients were adequatelymetabolized during the operation. The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.
Interventions
PROCEDUREProlonging the duration of postoperative endotracheal intubation before extubation.
The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.
Sponsors
Qilu Hospital of Shandong University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
1. Patients preoperatively diagnosed with resectable gastric cancer 2. Patients without distant organ metastasis 3. Patients with preoperative Overnight Cardiorespiratory Sleep Testing (OCST) or Polysomnography (PSG) results showing Apnea-Hypopnea Index (AHI) \>30 events/hour and SaO₂ \<80% 4. Patients with cardiopulmonary function deemed suitable for surgery 5. Patients aged 18-85 years 6. Patients who voluntarily joined this study and provided written informed consent
Exclusion criteria
1. Patients with a history of or concurrent other malignant tumors 2. Patients who underwent palliative resection 3. Subjects who experienced acute cardiovascular or cerebrovascular events (e.g., acute cerebral infarction, acute coronary syndrome) within the past 3 months, or whose cardiovascular clinical symptoms/diseases are not well-controlled 4. Patients with a history of psychotropic drug abuse that cannot be abstained, or those with psychiatric disorders 5. Patients with concomitant diseases that, in the investigator's judgment, seriously endanger the patient's safety or affect the completion of the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative complications | 48-72 hour | The incidence of postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea. |
Countries
China
Outcome results
None listed