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The Effect of Pursed-Lip Breathing Exercise on Anxiety and Physiological Parameters Post-Bronchoscopy in Patients With COPD: A Randomized Controlled Trial

The Effect of Purse-Lip Breathing Exercise on Anxiety and Physiological Parameters Post-Bronchoscopy in Patients With COPD: A Randomized Controlled Trial

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07361978
Enrollment
64
Registered
2026-01-23
Start date
2026-01-28
Completion date
2026-12-21
Last updated
2026-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD

Keywords

copd, pursed-lip breathing, Nursing care, anxiety

Brief summary

This randomized controlled trial investigates the effect of Pursed Lip Breathing (PLB) on anxiety levels and physiological parameters in patients with Chronic Obstructive Pulmonary Disease (COPD) following bronchoscopy. While PLB is known to improve oxygenation and ventilation in pulmonary rehabilitation, its specific impact on the immediate recovery period after bronchoscopy is understudied. The study aims to determine if nurse-led PLB intervention significantly improves heart rate, blood pressure, oxygen saturation, and reduces anxiety compared to standard care.

Detailed description

Chronic Obstructive Pulmonary Disease (COPD), which ranks among the leading causes of morbidity and mortality worldwide, is expected to have increasingly negative consequences. There are over 600 million COPD patients worldwide and approximately 2-3 million in Turkey. COPD requires a complex and long-term response that coordinates the contributions of a wide range of professionals, specific types of medication, and appropriate monitoring equipment, and this care should ideally be integrated into a system that promotes patient empowerment. The associated treatment process involves repeated hospital admissions, which impose high economic costs on countries. In the dynamic environment of critical care medicine, bedside bronchoscopy has emerged as a crucial diagnostic and therapeutic tool that bridges the gap between traditional pulmonary interventions and the urgent needs of critically ill patients. Bronchoscopy allows direct visualization of the airways and lung parenchyma and can be useful in evaluating various bronchopulmonary conditions and diseases, including foreign bodies, tumors, infectious and inflammatory processes, airway obstruction, and bronchopulmonary hemorrhage. Bronchoscopy may also be associated with other complications and discomforts beyond existing respiratory system problems. Teaching patients breathing exercises is another nursing intervention that can increase oxygenation and reduce dyspnea. Various breathing exercises are available, including PLB. PLB is a breathing technique used to improve oxygenation and ventilation. This breathing technique involves consciously inhaling through the nose, followed by a slow and controlled exhalation through pursed or pinched lips, which prolongs the exhalation phase compared to the normal inspiration-exhalation ratio. Nurses' ability to promptly recognize distress enables intervention teams to respond quickly and prevent further deterioration. The literature shows that pursed-lip breathing improves vital signs and oxygenation in COPD rehabilitation and during the recovery process after bronchoscopy. In a recent study, patients who practiced pursed-lip breathing during the post-bronchoscopy period showed significant improvements in parameters such as oxygen saturation, pulse rate, and blood pressure compared to the control group. However, studies examining the effect of this technique on anxiety and immediate physiological parameters in COPD patients during the bronchoscopy procedure are limited. This study was designed as a randomized controlled trial to determine the effect of PLB application on anxiety levels and physiological parameters (heart rate, blood pressure, oxygen saturation) in patients with COPD after bronchoscopy.

Interventions

OTHERPursed-Lip Breathing exercise and Routine Care

Pursed-Lip Breathing exercise will be done. Following a conscious inhalation through the nose, it involves exhaling slowly and in a controlled manner through pursed lips; this prolongs the exhalation phase compared to the normal inspiration-exhalation ratio.

Sponsors

Fenerbahce University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Patients diagnosed with COPD * Patients undergoing elective bronchoscopy under sedation * Patients aged 18 - 80 years * Patients who are fully oriented, conscious, and able to communicate

Exclusion criteria

* Patients undergoing emergency bronchoscopy * Patients with hemodynamic instability prior to the procedure (systolic blood pressure \<90 mmHg or \>180 mmHg) * Patients with severe hearing or cognitive impairment

Design outcomes

Primary

MeasureTime frameDescription
Change in State Anxiety LevelBaseline (Pre-procedure) and immediately after the bronchoscopy procedure (up to 30 minutes).Anxiety levels will be assessed using the State-Trait Anxiety Inventory (STAI), specifically the State Anxiety subscale (STAI-S). The scale consists of 20 items. Total scores range from a minimum of 20 to a maximum of 80. Higher scores indicate higher levels of anxiety (worse outcome), while lower scores indicate lower levels of anxiety.

Secondary

MeasureTime frameDescription
Change in Oxygen Saturation (SpO2)Baseline, during the procedure, and immediately after the procedure. Baseline, during the procedure, and immediately after the procedure. (30 minutes before and after the procedure.)Measured via pulse oximetry. Values are recorded as a percentage (%). Higher values indicate better physiological oxygenation status. Unit of measure: Percentage of oxygen saturation
Change in Heart RateBaseline, during the procedure, and immediately after the procedure (up to 30 minutes).Measured via pulse oximetry or cardiac monitor. Values are recorded as beats per minute (bpm). Lower values (within normal range) generally indicate lower physiological stress.
Change in Systolic Blood PressureBaseline (pre-procedure), during the procedure, and immediately after the procedure (up to 30 minutes).Measured via non-invasive blood pressure cuff. Values are recorded in millimeters of mercury (mmHg).
Change in Diastolic Blood PressureBaseline (pre-procedure), during the procedure, and immediately after the procedure (up to 30 minutes).Measured via non-invasive blood pressure cuff. Values are recorded in millimeters of mercury (mmHg).

Countries

Turkey (Türkiye)

Contacts

CONTACTRuhat Tilki, PhD Candidate
ruhat.tilki@fbu.edu.tr+90 553 514 98 10

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026