Comparison Between Different Types of Flexible Ureteroscopes

A Comparative Study of Performance and Cost-effectiveness of Three Different Single-Use Flexible Ureteroscopes in the Management of Renal Stones: A Randomized Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07360353

Acronym

FURS

Enrollment

180

Registered

2026-01-22

Start date

2026-01-25

Completion date

2026-09-01

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephrolithiasis, Renal Calculi

Keywords

Flexible ureteroscopy, Single-use flexible ureteroscope, Renal stones

Brief summary

The current study aims to compare the performance of three distinct single-use digital flexible ureteroscope types in terms of cost-effectiveness, postoperative complications, operating time, and stone-free rates (SFRs).

Detailed description

Retrograde intrarenal surgery (RIRS) is the preferred treatment modality for renal stones measuring less than 20 millimeters (mm). Several types of flexible ureteroscopes are currently available on the market from different manufacturers. However, there is a shortage of comparative studies evaluating the performance of different single-use flexible ureteroscopes. This study aims to compare the performance of three different single-use digital flexible ureteroscopes in terms of cost-effectiveness, postoperative complications, operative time, and stone-free rates (SFRs).

Interventions

DEVICELithoVue™ (Boston Scientific Corporation)

Participants randomized to this arm will undergo retrograde intrarenal surgery (RIRS) for renal stone management using the LithoVue™ single-use digital flexible ureteroscope.

DEVICEWiScope® (OTU Medical Inc. (Silicon Valley, USA))

Participants randomized to this arm will undergo retrograde intrarenal surgery (RIRS) for renal stone management using the WiScope single-use digital flexible ureteroscope.

DEVICESingle-Use Ureterorenoscope (Scivita Medical Technology Co., Ltd.)

Participants randomized to this arm will undergo retrograde intrarenal surgery (RIRS) for renal stone management using the single-use digital flexible ureterorenoscope manufactured by Scivita Medical Technology Co., Ltd.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Patients aged 18 to 60 years. * Presence of renal stones measuring less than 20 millimeters (mm).

Exclusion criteria

* Renal stones larger than 20 millimeters (mm). * Uncontrolled bleeding disorders or coagulopathies. * Active urinary tract infection. * Renal failure. * Uncontrolled diabetes mellitus, hypertension, or hepatic dysfunction. * Pregnancy. * Abnormal urinary tract anatomy or known ureteric stricture. * History of previous open ureteric surgery.

Design outcomes

Primary

Measure	Time frame	Description
Cost-effectiveness of single-use flexible ureteroscopes	4 weeks postoperatively	Comparison of total procedural cost and stone-free rate among three single-use flexible ureteroscopes used in retrograde intrarenal surgery (RIRS).

Secondary

Measure	Time frame	Description
Operative Time and Postoperative Complications	up to 4 weeks postoperatively	Incidence of postoperative complications within the postoperative period.

Countries

Egypt

Contacts

CONTACTHesham E Khayrallah, Resident

heshamkhayrallah111@gmail.com+201016704043

CONTACTAshraf M Satour, Lecturer

+201050505463

PRINCIPAL_INVESTIGATORHesham E Khayrallah, Resident

Ain Shams University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026