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Internalized Symptoms in Adolescents With Autism Spectrum Disorder (ASD) and Typically Developing Adolescents : Gaining Insight Into Coping Strategies and the Psychological Processes Involved

Internalized Symptoms in Adolescents With Autism Spectrum Disorder (ASD) and Typically Developing Adolescents : Gaining Insight Into Coping Strategies and the Psychological Processes Involved

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07360223
Enrollment
252
Registered
2026-01-22
Start date
2026-02-01
Completion date
2031-12-31
Last updated
2026-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Spectrum Disorder (ASD)

Keywords

ASD coping

Brief summary

Introduction: Adolescents with autism spectrum disorder (ASD) have more mental health problems than typically developping adolescents (without ASD). Coping strategies are a key concern for adolescents with ASD in managing depressive and anxiety symptoms. Currently, few studies have examined the coping strategies used by adolescents with ASD. The methodological considerations underscore the need for an assessment method tailored to adolescents with ASD. Finally, although current data are still limited, the results suggest that there may be differences between the coping strategies used by adolescents with ASD and typically developing adolescents, thus calling for more in-depth comparative research. Objectives: This study aims to validate a coping strategies assessment method adapted for adolescents with ASD (1) and to examine coping strategies associated with internalizing symptoms (2) Population: 252 participants: 84 adolescents with ASD (1), 84 adolescents with autistic traits but no clinical diagnosis of ASD (2), and 84 typically developing adolescents (3). The age range is 12-17 years. Study design: The study is divided into two parts: a cross-sectional part (T) and a longitudinal part (L). * The cross-sectional part will include three meetings spread over a period of approximately three months (approximately one meeting per month). * The longitudinal part will consist of a meeting scheduled one year after the last meeting of the cross-sectional part.

Interventions

Participants will complete questionnaires and take part in a semi-structured interview

Sponsors

Université Catholique de Louvain
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
12 Years to 17 Years
Healthy volunteers
Yes

Inclusion criteria

* 12-17 years * speak french fluently

Exclusion criteria

* Intellectual disability

Design outcomes

Primary

MeasureTime frameDescription
Coping strategiesThroughout the entire study, approximately during 5 yearsMeasure by questionnaire and semi-structured interviews. Questionnaire : Coping Strategies Inventory (CSI) The questionnaire is designed to identify coping strategy profiles. It includes 8 sub-strategies (Problem solving, Cognitive restructuring, Express Emotions, Social Support, Problem avoidance, Wishful thinking, Self-Criticism, Social Withdrawal) and does not have strict minimum or maximum scores. Instead, it provides an overview of the relative use of each coping strategy

Secondary

MeasureTime frameDescription
Anxious, depressive and somatic symptomsThroughout the entire study, approximately during 5 yearsMeasure by questionnaire Questionnaire : Revised Children's Anxiety and Depression Scale (RCADS) T-score \< 65 → Non-clinical range. Symptoms are minimal or within the typical range compared to the normative population. No clinical concern is indicated T-score ≥ 65 → Borderline/clinically elevated Symptoms are higher than average and may indicate potential anxiety or depression issues. T-score ≥ 70 → Clinically significant range Symptoms are substantially elevated compared to peers. There is a high likelihood of clinically meaningful anxiety or depression

Contacts

CONTACTHéloïse HL Louvegny, PhD Student
heloise.louvegny@uclouvain.be010 47 80 60
CONTACTStéphanie SM Mazzone, Postdoctoral
stephanie.mazzone@saintluc.uclouvain.be02 764 20 34
PRINCIPAL_INVESTIGATORNathalie NNG Nader-Grosbois, Professor

Université Catholique de Louvain (UCLouvain)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026