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Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery.

Determination the Safety of Disaggregant and Anticoagulant Therapy in the Development of Complications in Noncardiac Vascular Surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07358416
Enrollment
500
Registered
2026-01-22
Start date
2025-05-01
Completion date
2026-02-28
Last updated
2026-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleeding, Cerebral Hypoxia During and/or Resulting From A Procedure, Thrombosis

Keywords

Vascular surgery, Antiplatelet, Anticoagulants, complication, trombosis, bleeding

Brief summary

The goal of this retrospective clinical trial is to find out association antiplatelet and anticoagulant therapy with perioperative complications in non-cardiac vascular surgery in patients . The main questions it aims to answer are: Does the use of antiplatelet agents and anticoagulants affect the development of complications in the perioperative period during operations on the main arteries? Does discontinuing antiplatelet and anticoagulant medications affect the development of perioperative complications in major artery surgeries?? Researchers will compare with patients who didn't use antiplatelets and anticoagulant drugs to see ift he incidence of complications comparable? This is a retrospective study based on the analysis of medical records (case histories).

Interventions

DRUGAspirin

Patients who take aspirin until the operation day

DRUGClopidogrel

Patients who take clopidogrel until the operation day

DRUGTicagrelor

Patients who take ticagrelor until the operation day

DRUGDabigatran

Patients who take dabigatran until the operation day

DRUGRivaroxaban

Patients who take rivaroxaban until the operation day

DRUGApixaban

Patients who take apixaban until the operation day

DRUGWarfarin

Patients who take warfarin until the operation day

Patients who take aspirin and clopidogrel until the operation day

Patients who take aspirin and ticagrelor until the operation day

DRUGAspirin + Apixaban

Patients who take aspirin and apixaban until the operation day

DRUGAspirin + rivaroxaban

Patients who take aspirin and rivaroxaban until the operation day

DRUGClopidogrel + Apixaban

Patients who take clopidogrel and apixaban until the operation day

DRUGClopidogrel + Rivaroxaban

Patients who take clopidogrel and rivaroxaban until the operation day

Sponsors

Petrovsky National Research Centre of Surgery
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients who received surgical treatment on the main arteries.

Exclusion criteria

* Patients who received surgical treatment on the main veins.

Design outcomes

Primary

MeasureTime frameDescription
BleedingFirst 24 hours after operationCase of bleeding or haematoma development

Secondary

MeasureTime frame
TrombosisFirst 24 hours after operation

Countries

Russia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026