Effect of Topical Argan Oil on Healing After Laser Depigmentation.

Comparative Evaluation of Argan Oil as a Post-Operative Agent Versus Placebo Following Laser Gingival Depigmentation: A Randomized Controlled Clinical Trial

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07357883

Enrollment

Registered

2026-01-22

Start date

2025-10-29

Completion date

2026-01-10

Last updated

2026-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Hyperpigmentation, Laser Depigmentation, Postoperative Gingival Healing, Topical Argan Oil

Keywords

Laser depigmentation, postoperative healing, topical argan oil

Brief summary

Effect of Argan oil vs placebo on healing after laser depigmentation

Detailed description

Evaluate the effect of Argan oil vs. placebo on post-operative healing after laser depigmentation. as well as Compare pain levels (VAS score), gingival pigmentation recurrence, and patient satisfaction between groups at predetermined follow-up intervals.

Interventions

PROCEDURELaser Depigmentation

Laser protocol: Diode laser, wavelength 810-980 nm, continuous mode, initiated fiber tip 400 µm, power 1.5-2 W.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients aged 18-40 with moderate/severe physiological gingival pigmentation * Good general and periodontal health.

Exclusion criteria

* Systemic diseases affecting healing (e.g., uncontrolled diabetes). * Smokers or tobacco chewers. * Pregnant/lactating women. * Previous depigmentation procedures in the last 2 years.

Design outcomes

Primary

Measure	Time frame	Description
Effect of Argan oil	14 days	Evaluate the effect of Argan oil vs. placebo on post-operative Gingival healing

Secondary

Measure	Time frame	Description
Visual Analog Scale (VAS)	14 days	Compare pain levels (VAS score) , gingival pigmentation recurrence, and patient satisfaction between groups.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026