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Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism

Short- Term Outcome and One -Year Recurrence in Acute Pulmonary Embolism Patients With and Without Sleep - Disordered Breathing

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07356908
Enrollment
40
Registered
2026-01-21
Start date
2025-01-01
Completion date
2026-01-01
Last updated
2026-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Embolism, Sleep Apnea Syndrome (OSAS)

Keywords

pulmonary embolism, sleep apnea

Brief summary

This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.

Detailed description

This prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CT pulmonary angiography and followed up with sllep study to asses the effect of sleep related breathing disorderon the recurrence of emboli.

Interventions

DIAGNOSTIC_TESTpolysomnography

This prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CTPA

Sponsors

Alexandria University
Lead SponsorOTHER
University of Alexandria
CollaboratorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age≥18years. * Objectively confirmed acute pulmonary embolism by computed tomography pulmonary angiography (CTPA). * Hemodynamically stable or clinically stabilized within 72 hours of admission. .Ability to provide informed consent.

Exclusion criteria

.Known central sleep apnea without obstructive features. .Inabilityto undergo sleep study evaluation. * Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
Pulmonary embolism recurrence12 monthsocuurence of pulmonary embolism during the follow up period confirmed by CTPA
Recurrence of Pulmonary EmbolismONE YEARoccurence of objectively confirmed pulmonary embolism during the one t=year follow up period confirmed by CTPA

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026