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Occlusal Adjustments Needed for Michigan Splints Made Using Different Digital Bite Records

The Assessment of The Volumetric Occlusal Adjustments Required for Michigan Splints Fabricated Using Various Digital Bite Registrations

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07356622
Acronym
AVOAMSDBR
Enrollment
10
Registered
2026-01-21
Start date
2024-03-01
Completion date
2025-12-15
Last updated
2026-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular Disorders (TMD)

Keywords

Digital occlusal recording, Digital bite registration, Occlusal splint fabrication, Occlusal splint accuracy, Michigan splint, Digital facebow, Virtual articulator, Three-dimensional printing

Brief summary

This clinical study evaluated digital occlusal recording methods used in the fabrication of Michigan occlusal splints. The objective was to assess whether different digital bite registration techniques influenced the accuracy of occlusal splints and the amount of occlusal adjustment required at clinical fitting. Participants underwent digital bite registration procedures and received Michigan occlusal splints fabricated using different digital workflows. Follow-up visits were conducted for splint fitting and occlusal assessment. Participant safety and data confidentiality were maintained throughout the study, and all required ethical approvals and risk assessments were obtained prior to study initiation. The study findings were intended to support improvements in digital dental workflows and enhance the accuracy and efficiency of occlusal splint fabrication.

Detailed description

Background Temporomandibular disorders represented a common clinical condition affecting mandibular function and were frequently associated with parafunctional activities such as bruxism or clenching. Clinical features included orofacial pain, joint sounds, restricted mandibular movement, headaches, dental wear, and occlusal instability. Occlusal splints were commonly prescribed to reduce occlusal loading, protect dental structures, and establish a more favourable mandibular position. Conventional occlusal splint fabrication relied on physical impressions, mechanical articulation, and manual occlusal adjustment. These processes were time-consuming and technique-sensitive. Digital dentistry introduced alternative workflows incorporating intraoral scanning, virtual articulation, and computer-aided design and manufacturing, with the aim of improving accuracy, reproducibility, and efficiency. Accurate digital recording of the maxillomandibular relationship remained a critical factor influencing occlusal outcomes. Digital bite registration techniques performed at intercuspal position or centric relation, with or without digital facebow transfer, were expected to affect occlusal accuracy and the extent of chairside adjustment required at delivery. Virtual articulators were developed to simulate mandibular movements using digitally acquired data. These systems required accurate digital impressions, occlusal records, and appropriate orientation of the maxillary arch relative to craniofacial reference planes. Digital facebow systems enabled virtual transfer of maxillary position and were expected to improve mounting accuracy compared with average-value articulators alone. Study objectives Primary Objectives * To evaluate volumetric changes on the occlusal surfaces of Michigan splints following clinical adjustment. * To compare pre-adjustment and post-adjustment occlusal surface volumes across different digital workflows. * To assess whether an average-value virtual articulator produced occlusal splints at an increased occlusal vertical dimension without the need for clinical registration. Secondary objectives * To assess laboratory efficiency and quality control associated with digital workflows. * To evaluate clinical time and effort required for occlusal adjustment. * To assess participant comfort during digital recording procedures. This was a single-centre clinical study involving 10 participants. Each participant received four Michigan occlusal splints, corresponding to four different digital design workflows based on mandibular recording position and the inclusion or exclusion of a digital facebow record. Each of the four digital designs generated for every participant was manufactured as a separate occlusal splint, resulting in four splints per participant. Clinical and laboratory procedures Visit 1 * Informed consent was obtained. * Standardised dental photography was performed. * A digital facebow record was obtained using a digital facebow system equipped with a scannable bite fork (Axiopresia) as part of the registration process, where applicable. The scannable bite fork was positioned intraorally and digitally captured to record the spatial relationship of the maxillary arch relative to craniofacial reference planes. * Digital impressions of the maxillary and mandibular arches were obtained using an intraoral scanner under standardised clinical conditions. * Bite registration at centric relation/ retruded articulation position was obtained following neuromuscular deprogramming using a Lucia gauge and intraoral scanner. * Bite registration at intercuspal position was recorded using the intraoral scanner. Laboratory procedures Using computer-aided design software, four distinct digital occlusal splint designs were produced for each participant based on different combinations of mandibular recording position and digital facebow transfer: Retruded articulation position (centric relation) with digital facebow record Retruded articulation position (centric relation) without digital facebow record Intercuspal position with digital facebow record Intercuspal position without digital facebow record Each digital design was generated using the same virtual articulator parameters and identical splint design settings, differing only in the mandibular position record and the inclusion or exclusion of the digital facebow data. The resulting designs were then manufactured using three-dimensional printing. Visit 2: Fitting and occlusal adjustment * Clinical fitting of the occlusal splints was performed during the second visit. * Occlusal adjustments were carried out to achieve balanced light occlusal contacts at the resting intercuspal position. * Lateral movements were assessed to confirm canine guidance, and anterior guidance was evaluated during protrusive movements. * Any occlusal interferences were identified and removed accordingly to achieve a stable and harmonious occlusal scheme. * Following completion of occlusal adjustments, the splints were digitally scanned via lab scanner for post-adjustment analysis. Outcome assessment Pre-adjustment and post-adjustment digital scans of each occlusal splint were imported into three-dimensional analysis software ( Geomagic software). Root mean square deviation values were calculated following best-fit alignment to quantify volumetric changes associated with occlusal adjustment. The 3D and 2D Comparisons at six sections were done ( middle of the cingulum of the right and left central incisor, middle of the cingulum of the right and left canines, messy-buccal cusp to disco-palatal cup of the right and left first molar). Occlusal deviation maps were standardised using consistent colour scales to allow comparison between workflows.

Interventions

DEVICERetruded axis position(RAP with) without a digital facebow

The intervention involves the fabrication of Michigan occlusal splints using different digital bite registration workflows. Each participant undergoes digital occlusal recording in centric relation (CR) and intercuspal position (ICP), with and without the use of an Axioprisa® digital facebow, and articulation is performed using Axioprisa® virtual articulator. Four splints are fabricated per participant based on these recordings. Participants are blinded to the recording method used for each splint and try all splints in a crossover manner. Occlusal accuracy and adjustment requirements are evaluated using three-dimensional surface superimposition and root mean square (RMS) deviation analysis.

DEVICEDigital face-bow, digital bite registration, digital scanning

The intervention involves the fabrication of Michigan occlusal splints using different digital bite registration workflows. Each participant undergoes digital occlusal recording in centric relation (CR) and intercuspal position (ICP), with and without the use of an Axioprisa® digital facebow, and articulation is performed using Axioprisa® virtual articulator. Four splints are fabricated per participant based on these recordings. Participants are blinded to the recording method used for each splint and try all splints in a crossover manner. Occlusal accuracy and adjustment requirements are evaluated using three-dimensional surface superimposition and root mean square (RMS) deviation analysis.

DEVICEDigital facebow, digital bite registration, digital scanning

The intervention involves the fabrication of Michigan occlusal splints using different digital bite registration workflows. Each participant undergoes digital occlusal recording in centric relation (CR) and intercuspal position (ICP), with and without the use of an Axioprisa® digital facebow, and articulation is performed using Axioprisa® virtual articulator. Four splints are fabricated per participant based on these recordings. Participants are blinded to the recording method used for each splint and try all splints in a crossover manner. Occlusal accuracy and adjustment requirements are evaluated using three-dimensional surface superimposition and root mean square (RMS) deviation analysis.

Sponsors

King's College London
Lead SponsorOTHER
Guy's Hospital
CollaboratorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Subject)

Masking description

Participants are blinded to the type of digital bite registration method used to fabricate each of the four Michigan occlusal splints. Each participant is required to try four splints in a crossover manner, with splints coded and presented in identical appearance so that participants cannot distinguish which recording method was used for any given splint. Clinicians and researchers involved in splint fabrication and assessment are not blinded.

Intervention model description

Participants undergo multiple digital bite registration procedures. Michigan occlusal splints fabricated using each method are assessed within the same participant, allowing within-subject comparison of occlusal accuracy and root mean square (RMS) deviation.

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

• * Aged between 18 and 65. * Able to provide informed consent. * Have no more than one tooth missing per quadrant.

Exclusion criteria

* Patients with removable dentures * Patients receiving medication for psychological disorders. * Patients diagnosed with systemic joint disorders. * Pregnant. * Patients who have received TMD treatment in the last 6 months. * Deep bite cases. * Those who have an extreme class 3 dental or skeletal relationship.

Design outcomes

Primary

MeasureTime frameDescription
Volumetric occlusal adjustment of michigan occlusal splintsBaseline (pre-adjustment) and at splint fitting (post-adjustment)The primary outcome was the volume of occlusal adjustment required for Michigan occlusal splints fabricated using different digital bite registration workflows. Volumetric changes were quantified by calculating root mean square (RMS) deviation values between pre-adjustment and post-adjustment digital scans of each splint using three-dimensional surface comparison software. Higher RMS values indicated greater occlusal adjustment.

Secondary

MeasureTime frameDescription
Occlusal contact quality after adjustment of michigan occlusal splintsAt splint fitting visitThe secondary outcome was the qualitative assessment of occlusal contact quality following clinical adjustment of Michigan occlusal splints fabricated using different digital workflows. Occlusion was assessed clinically to confirm balanced light contacts at the resting intercuspal position, presence of canine guidance during lateral excursions, presence of anterior guidance during protrusive movements, and elimination of occlusal interferences. Outcomes were recorded as achievement of a stable and clinically acceptable occlusal scheme following adjustment.

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026