Robotic vs Open Nephrectomy for ADPKD

Robotic-assisted Unilateral Nephrectomy for Autosomal Dominant Polycystic Kidney

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07355114

Acronym

ADPKDR-O

Enrollment

Registered

2026-01-21

Start date

2023-01-01

Completion date

2028-01-01

Last updated

2026-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Keywords

ADPKD

Brief summary

The goal of this observational prospective cohort study is to evaluate the feasibility, safety, and postoperative outcomes of robotic-assisted unilateral native nephrectomy using the Medtronic Hugo™ RAS system compared with the open surgical approach in patients with autosomal dominant polycystic kidney disease (ADPKD) The main question(s) it aims to answer are: Is robotic-assisted unilateral nephrectomy with the Hugo™ RAS system feasible and safe in patients with ADPKD? Does robotic-assisted nephrectomy provide comparable or improved postoperative outcomes (e.g., complications, transfusion rates, length of hospital stay) compared with open nephrectomy? Researchers will compare robotic-assisted unilateral nephrectomy (Hugo™ RAS) with open unilateral nephrectomy to see if the robotic approach results in similar morbidity with shorter hospital stay, despite longer operative times. Participants are adult patients with ADPKD undergoing unilateral native nephrectomy at a single tertiary transplant center, most of whom have end-stage renal disease and are candidates for or recipients of kidney transplantation. Both male and female patients were included; patients undergoing bilateral nephrectomy were excluded.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult Patients who underwent unilateral nephrectomy for ADPKD

Exclusion criteria

* Patients who underwent bilateral nephrectomy for ADPKD were excluded from the study.

Design outcomes

Primary

Measure	Time frame	Description
Mortality by 90 day	By 90 days	Mortality by 90 day

Secondary

Measure	Time frame	Description
Postoperative complications	By 90 days	Postoperative complications described by Clavien-Dindo Classification

Countries

Italy

Outcome results