Endodontic Infection, Periapical Periodontitis
Conditions
Brief summary
You are being asked to participate in this research study because you are being treated at the UCSF Graduate Endodontics department for an endodontic procedure. We are trying to determine the treatment outcomes of one v. two-visit endodontic treatments. .If you decide to continue, we would like to request your consent for a follow up period of 1 year to observe the healing of the abscess. Observation periods occur at 6 months following the completion of the root canal and at 12 months and are a part of the standard of care. We will review findings in the Axium chart, which will be recorded by the treating doctor
Detailed description
This research study includes patients who are receiving endodontic treatment within the UCSF Graduate Endodontics Department. The purpose of the study is to evaluate and compare treatment outcomes between one-visit and two-visit root canal procedures. Participants who choose to continue in the study will be followed for a period of one year so that healing of the periapical abscess can be monitored. Follow-up appointments are scheduled at six months and twelve months after treatment completion, both of which are part of routine standard care. Clinical and radiographic findings documented in the Axium chart by the treating provider will be reviewed as part of the study analysis.
Interventions
calcium hydroxide will be used as interim medication in the first visit and patients will return for the obturation in the second visit.
OTHERcontrol group
control group- no intervention
Sponsors
University of California, San Francisco
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Classified as American Society of Anesthesiologists (ASA) Class I or II * presenting with radiographic evidence of apical periodontitis-defined as a Cone-Beam Computed Tomography Periapical Index (CBCTPAI) score of 3 or greater according to the Estrela classification
Exclusion criteria
*
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical and Radiographic Healing | 12 months | The primary outcome was defined using a combined clinical and radiographic healing based on the Cone-Beam Computed Tomography Periapical Index (CBCT-PAI) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Volumetric Change in Periapical Lesion Size | 12 months | The secondary outcome was defined as the change in lesion volume (mm³) between baseline and follow-up CBCT scans, serving as a quantitative metric of periapical healing |
Countries
United States
Outcome results
None listed