Ultrasound-Guided Versus Laparoscopy-Guided Transversus Abdominis Plane Block for Postoperative Analgesia

Comparison of the Efficacy of Ultrasound-Guided and Laparoscopy-Guided Transversus Abdominis Plane(TAP) Block on Postoperative Analgesia in Patients Undergoing Laparoscopic Upper Abdominal Surgery

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07352189

Acronym

US-LTAP

Enrollment

Registered

2026-01-20

Start date

2023-01-11

Completion date

2023-06-15

Last updated

2026-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain Management

Keywords

Transversus Abdominis Plane Block, TAP block, Postoperative Pain, analgesia

Brief summary

This prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic upper abdominal surgery under general anesthesia. Postoperative pain scores, analgesic consumption and recovery parameters were evaluated during the first 24 hours after surgery.

Detailed description

Patients aged 18-70 years with ASA physical status I-III who were scheduled for laparoscopic upper abdominal surgery under general anesthesia were included in the study. After induction of anesthesia, patients were randomly assigned to one of two group, bilateral subcostal transversus abdominis plane block was performed under ultrasound-guidance using a local anesthetic mixture before extubation. In the laparoscopy-guided group, bilateral subcostal transversus abdominis plane block was performed under laparoscopic guidance using the same local anesthetic mixture before abdominal closure. Postoperative pain intensity was assessed by using the Numeric Rating Scale (NRS). Total opioid consumption, time to first analgesic requirement, paracetamol consumption, postoperative nausea and vomiting, length of hospital stay, time to ambulation and time to gastrointestinal recovery were recorded during the first 24 hours after surgery. Complications related to the TAP block were also evaluated.

Interventions

PROCEDUREUltrasound-guided Transversus Abdominis Plane (US-TAP) Block

Bilateral ultrasound-guided subcostal transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL0.25% bupivacaine and 10 ml of 1% lidocaine).

PROCEDURELaparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block

Bilateral laparoscopy-guided transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL 0.25% bupivacaine and 10 ml of 1% lidocaine).

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patients aged 18-70 yeras * ASA physical status I-III * Scheduled for laparoscopic upper abdominal surgery * Provided written informed consent

Exclusion criteria

* Patient refusal * Allergy to local anesthetics * Coagulopathy * Infection at the injection site * Severe systemic disease * ASA physical status IV-V

Design outcomes

Primary

Measure	Time frame	Description
Postoperative pain score (NRS)	First 24 hours postoperatively	Postoperative pain intensity measured using the Numeric Rating Scale (NRS), a 0-10 scale where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicates worse pain.

Countries

Turkey (Türkiye)

Contacts

PRINCIPAL_INVESTIGATORTalat Ercan E Şerifsoy, MD

Maltepe University Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026