Hypertension With Hypertriglyceridemia
Conditions
Keywords
Rosemary infusion, hypertension , Hypertriglyceridemia
Brief summary
This study aimed to evaluate the effects of daily rosemary infusion consumption on blood pressure and lipid profile in patients with mild hypertension, stratified by triglyceride status. This 6-week open-label interventional study enrolled 47 patients with mild hypertension (systolic BP 140-159 mmHg and/or diastolic BP 90-99 mmHg). Participants were stratified into two groups: normal triglycerides, TG \<1.7 mmol/L, n=22 and high triglycerides, TG ≥1.7 mmol/L, n=25. Blood pressure was assessed using 24-hour ambulatory monitoring (Holter) at baseline and day 45. Comprehensive biochemical analysis included lipid profile, hepatic and renal function markers, and inflammatory parameters.
Interventions
Rosemary infusion 100 ml during 45 days
Rosemary infusion 100 ml during 45 days
Sponsors
Study design
Eligibility
Inclusion criteria
Participants of both sexes, aged 18 years and older, were included in the study. The inclusion criteria were: (1) Presence of mild hypertension defined as systolic blood pressure (SBP) of 140-159 mmHg and/or diastolic blood pressure (DBP) of 90-99 mmHg according to the 2018 ESC/ESH guidelines(Williams et al., 2018); (2) No use of medications or dietary supplements for other health conditions.
Exclusion criteria
Participants were excluded if they had renal failure, autoimmune diseases, major gastrointestinal disorders, or a history of cardiovascular disease. Other
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure measurement | 45 days |
| Evolution of serum triglycerides | 45 days |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular disease risk assessment | 45 days |
| Atherogenic Index of Plasma | 45 days |
Countries
Tunisia