The Effect of Frailty on Hypotension After Anesthesia Induction

The Effect of Frailty in Geriatric Patients on Hypotension Observed After Anesthesia Induction

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07351552

Enrollment

Registered

2026-01-20

Start date

2026-01-15

Completion date

2026-06-15

Last updated

2026-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fraility, Hypotension

Brief summary

Frailty is defined as a state of weakness resulting from a decrease in physiological reserves due to physiological changes, diseases, and/or malnutrition associated with advancing age. Frail older adults face increased mortality, morbidity, and healthcare costs when exposed to stressors, making this issue increasingly important. The FRAIL Scale, developed by Morley et al. , is a 5-item measure that assesses frailty. The FRAIL Scale has been validated in many countries and has been proven to be an effective method for detecting frailty. This scale assesses the patient's fatigue, resistance, mobility, weight loss, and other diseases. In the 5-item FRAIL scale, patients receive 0 or 1 point based on their answers, and a total of 0 points is considered non-frail, 1-2 points is considered pre-frail, and \>2 points is considered frail. Frailty is associated with a higher risk of postoperative complications. Rothenberg and colleagues reported in a study involving more than 400,000 patients that frailty doubles the risk of postoperative complications . Hypotension following anesthesia induction is a common complication in geriatric patients. Decreased cardiopulmonary reserve with age leads to an exaggerated drop in blood pressure during induction . In this study, the investigators aimed to determine the effect of frailty level in geriatric patients on hypotension observed after anesthesia induction.

Interventions

None listed

Study design

Observational model

CASE_CROSSOVER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients who do not have difficulty communicating, * have good cognitive function, * scheduled for surgery under general anesthesia

Exclusion criteria

* Patients admitted for surgery in emergency situations * Patients with active malignancy * Patients with physical disabilities and impairments (limb amputations, stroke sequelae, unable to speak, hearing problems) * Patients with acute infections * Patients with acute illnesses (decompensated congestive heart failure, recent myocardial infarction/stroke, COPD exacerbation) * Patients who have been hospitalized or undergone surgery within the last month * Patients with advanced dementia * Patients who are unable to provide a medical history or cooperate

Design outcomes

Primary

Measure	Time frame
The effect of fragility level on hypotension observed after anesthesia induction	20 minutes

Contacts

CONTACTEmine ASLANLAR

draslanlar@gmail.com05556219830

Outcome results