Endobronchial Mass, Tuberculosis, Pulmonary
Conditions
Keywords
Fiberoptic bronchoscopy, Endobronchial TB, Smear negative TB, Suspected PTB
Brief summary
The aim of the present study is to evaluate the role of bronchoscopy in diagnosis of endobronchial tuberculosis in suspected pulmonary tuberculosis patients whose sputum samples are negative for Ziehl Neelsen stain.
Detailed description
Bronchoscopy plays a major role in identification and diagnosis of EBTB. As a general principal, Bronchoscopy -associated with microbiological testing- must be performed on patients whose CT examination results indicate EBTB. This study will try to focus on the importance of bronchoscopy in diagnosis of endobronchial tuberculosis among suspected pulmonary tuberculosis patients who undergo fiberoptic bronchoscope after being sputum Ziehl Neelsen negative, scarce sputum and/or persistent consolidation on chest radiograph (CXR).
Interventions
DIAGNOSTIC_TESTfiberoptic bronchoscopy evaluation of endobronchial features of TB
EBTB was classified into seven subtypes by using the Chung's method: actively caseating, fibrostenotic, oedematous-hyperaemic, tumorous, ulcerative, granular, and the non-specific bronchitic subtype.
Sponsors
Ain Shams University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* o Adults more than18 years. * Accept to participate. * Suspected pulmonary tuberculosis patients with three negative sputum samples are smear negative, and/or persistent consolidation on chest radiograph (CXR).
Exclusion criteria
* o Patients who refuse to participate in the study. * Patients who are sputum Ziehl Neelsen positive. * Patients who are diagnosed extrapulmonary tuberculosis. * Patients who are not fit for bronchoscopy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the role of fiberoptic bronchoscopy in sputum smear negative and radiologically suspected pulmonary tuberculosis 63 patients in Mansoura chest hospital, bronchoscopy unit for early detection of endobronchial tuberculosis. | 1 year | bronchoscopic evaluation of tracheobronchial tree for endobronchial tuberculosis lesions in patients with suspected PTB |
Secondary
| Measure | Time frame |
|---|---|
| The clinical presentation, bronchoscopic characteristics in comparison to radiological characteristics of EBTB, and incidence of EBTB subtypes in pulmonary TB patients | 1 year |
Countries
Egypt
Contacts
PRINCIPAL_INVESTIGATORHeba M Shalaby, MD
Ain Shams University, Faculty of medicine
Outcome results
None listed