Retrograde Intrarenal Surgery (RIRS) With High-Power Laser and Flexible, Navigable Suction Access Sheath (FANS) vs Mini-Percutaneous Nephrolithotomy (miniPCNL) for 2-3 cm Renal Stones

Flexible Ureterorenoscopy With High-Power Holmium: YAG Laser and Flexible, Navigable Suction Access Sheath vs Mini-Percutaneous Nephrolithotomy in 2-3 cm Kidney Stones Treatment: A Prospective Cohort Study

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07349992

Enrollment

Registered

2026-01-20

Start date

2022-06-01

Completion date

2024-06-01

Last updated

2026-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Stones, Nephrolithiasis

Brief summary

This prospective cohort study aims to compare the safety and efficacy of retrograde intrarenal surgery combined with a high-power Holmium:YAG laser and flexible navigable suction access sheath versus mini-percutaneous nephrolithotomy in patients with 2-3 cm renal stones.

Interventions

PROCEDURERetrograde Intrarenal Surgery

We performed retrograde intrarenal surgery combined with a high-power Holmium:YAG laser and flexible navigable suction access sheath in patients with 2-3 cm renal stones.

PROCEDUREMini Percutaneous Nephrolithotomy

We performed mini-percutaneous nephrolithotomy in patients with 2-3 cm renal stones.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥18 years * Kidney stones measuring 2-3 cm * Suitable for Retrograde Intrarenal Surgery (RIRS) or Mini-Percutaneous Nephrolithotomy (MiniPCNL) * Provided written informed consent

Exclusion criteria

* Pregnancy * Renal transplantation * Congenital renal anomalies * Uncorrectable coagulopathy

Design outcomes

Primary

Measure	Time frame
Stone-Free Rate	1 month

Secondary

Measure	Time frame
Hemoglobin change	postoperative first day
Fluoroscopy time	Perioperative
Complications	up to 4 weeks

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 13, 2026