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The Effect of Rhythmic Auditory Stimulation on VOR Gain Adaptation Among Healthy Adults - A Randomized Clinical Trial "VOR - Vestibulo-ocular Reflex"

Dancing Eyes: The Effect of Rhythmic Auditory Stimulation on VOR Gain Adaptation Among Healthy Adults - A Randomized Clinical Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07347470
Acronym
VOR
Enrollment
12
Registered
2026-01-16
Start date
2025-12-15
Completion date
2026-01-01
Last updated
2026-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Vestibular adaptation

Brief summary

The goal of this study is to learn whether adding rhythmic sound (a metronome beat or music) to eye-head exercises can improve the reflex that keeps vision clear during head movement. This reflex, called the vestibulo-ocular reflex (VOR), helps maintain visual stability during activities such as walking, turning, or bending. This type of training may help people with dizziness or balance problems, but this study focuses on healthy adults. The main questions addressed are: Does performing VOR exercises with a steady metronome beat improve the VOR more than performing the same exercises in silence? Does performing the exercises while listening to self-selected rhythmic music also improve the VOR, and is the effect better or worse than a metronome? Do the different sound conditions change how difficult the training feels or how dizzy participants feel? Three conditions will be compared: Silence: standard VOR training with no sound Metronome: training timed to a simple, steady beat Music: training performed while listening to self-selected music with a clear beat The study will assess whether adding rhythmic sound leads to greater improvement in VOR gain and whether one type of sound is more effective than another. Participants are healthy adults. Participants will: Attend the laboratory for three separate visits, each with a different sound condition (silence, metronome, and music). Visits will be at least 48 hours apart. Wear specialized goggles that record eye and head movements (EyeSeeCam). Perform brief eye-head tests before and after training, consisting of rapid head turns while maintaining fixation on a visual target. Complete 15 minutes of Incremental VOR adaptation training during each visit, repeating rapid head turns while fixating on a laser projected target (StableEyes). In some sessions movements will be synchronized to a metronome or music. Rate perceived training difficulty, ease of following the rhythm, and any dizziness or discomfort. By comparing results across the three conditions within the same participants, the study will determine whether a simple, low-cost rhythmic cue can enhance the effects of standard VOR exercises without increasing discomfort.

Interventions

the same 15 minutes of vestibular adaptation training will be completed by all participants in 3 different conditions: silence, metronome, and music. participants will be instructed to synchronize their head impulses to the beat in the auditory conditions.

OTHERSilence

15 minutes of vestibular adaptation training without any background noise.

Sponsors

University of Haifa
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

Participants will undergo vestibular adaptation training in 3 different conditions at least 48 hours apart - Silence, Metronome, and Music. the order will be randomly allocated.

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy

Exclusion criteria

* Vestibular disorders. Neurologic conditions, Deafness, Blindness

Design outcomes

Primary

MeasureTime frameDescription
Change in horizontal semicircular canal VOR gain for active and passive head impulsesGains values- Baseline (pre-training) and immediately after each training session (post-training). Assessed during each of the three sessions. The sessions are separated by at least 48 hours and all three will be completed over approximately 2 - 4 weeks.The change in vestibulo-ocular reflex (VOR) gain for the horizontal semicircular canals, measured using video head impulse testing (vHIT), calculated as the difference between pre-training and post-training gain values for both active and passive head impulses under each auditory condition (Silence, Metronome, and Music).

Secondary

MeasureTime frameDescription
Self-reported training difficulty and adverse symptomsImmediately after completion of each of the three training sessions. Sessions will be separated by at least 48 hours and all three will be completed over approximately 2-4 weeks.Participant-reported ratings of training difficulty and adverse symptoms (including dizziness and nausea), assessed using 1-10 visual analog scales completed after each training session under each of the three auditory conditions.

Countries

Israel

Contacts

CONTACTOfir Nesichi, M.D
ofir.nesichi@gmail.com586970711
CONTACTYoav Gimmon, P.T. Ph.D
yoavgimmon@gmail.com506442243

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026