1ry Versus 2ry ILM Peeling in RD

Primary Versus Secondary Internal Limiting Membrane Peeling in Uncomplicated Retinal Detachment

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07346560

Enrollment

100

Registered

2026-01-16

Start date

2025-12-15

Completion date

2027-03-01

Last updated

2026-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ILM Peeling, Retinal Detachment Rhegmatogenous

Keywords

Retinal detachment, ILM peeling, Proliferative vitroretinopathy

Brief summary

Patients with uncomplicated rhegmatogenous retinal detachment will be recruited. All eyes will underwent 23G PPV with silicon oil tamponade. The eyes will be classified into two groups according to the timing of ILM peeling. Group A, ILM peelin will be performed during the first intervention, while in group B, it will be done at the time of silicon oil extraction.

Interventions

PROCEDUREPrimary ILM peeling

ILM peeling during the 1st surgical intervention for rRD

PROCEDURESecondary ILM peeling

ILM peeling is delayed for the time of silicon oil extraction

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with uncomplicated rhegmatogenous retinal detcahment.

Exclusion criteria

* PVR * Recurrent RD * Tractional RD * Macular hole RD * Scleral buckling is indicated * Macular scarring * Previous PPV

Design outcomes

Primary

Measure	Time frame
Incidence of complications	From enrollment till 3 months postoperative

Countries

Egypt

Contacts

CONTACTAlaa Sinjab, MD

alaa.abdelsadek@med.sohag.edu.eg+20-01064037382

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026