Panniculitis in Dermatomyositis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07345949

Acronym

PANNICUL

Enrollment

Registered

2026-01-16

Start date

2025-10-20

Completion date

2028-04-20

Last updated

2026-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dermatomyositis, Panniculitis

Keywords

Panniculitis, Dermatomyositis, Adipose tissue

Brief summary

Adipose tissue involvement is rare in dermatomyositis. The occurrence of partial or diffuse lipodystrophy is a rare but well-characterized manifestation, particularly in juvenile forms of dermatomyositis. Panniculitis, on the other hand, is exceptional and rarely described in the literature, mostly in the form of clinical cases. Panniculitis in dermatomyositis is exceptional. There are no validated diagnostic criteria or treatment recommendations. Treatment is based, by analogy, on the therapeutic strategy for lupus panniculitis and involves synthetic antimalarials combined with steroids and/or immunosuppressants. The aim of this study is to describe panniculitis in dermatomyositis in order to determine whether there are clinical or histological characteristics that distinguish it from other causes of panniculitis, particularly panniculitis associated with lupus erythematosus.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Years to No maximum

Healthy volunteers

Inclusion criteria

* Subject aged 1 year and older * With a confirmed diagnosis of dermatomyositis * With a confirmed diagnosis of panniculitis

Exclusion criteria

* Panniculitis for which another cause has been established, particularly infectious and metabolic panniculitis

Design outcomes

Primary

Measure	Time frame	Description
Determine the clinical and histological characteristics of panniculitis in dermatomyositis	Up to 30 months	The investigators aim to describe: how inflammation of the subcutaneous fat manifests * in individuals with dermatomyositis * both: * clinically and visually in the patient * under the microscope (histology)

Countries

France

Contacts

Primary ContactDan LIPSKER, MD

dan.lipsker@chru-strasbourg.fr33 3 88 11 50 48

Outcome results