Gingival Recession, Localized
Conditions
Brief summary
Comparison of Volume-Stable Collagen Matrix, Platelet-Rich Fibrin, and Subepithelial Connective Tissue Graft in the Treatment of Multiple Adjacent Gingival Recessions: A Parallel-Group, Randomized, Controlled Clinical Trial
Interventions
BIOLOGICALVolume-Stable Collagen Matrix
Volume-Stable Collagen Matrix
Sponsors
Bulent Ecevit University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Intervention model description
A Parallel-Group, Randomized, Controlled Clinical Trial
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
were as follows: 1. ≥2 mm buccal recessions affecting ≥2 adjacent maxillary teeth; 2. systemically and periodontally healthy; 3. non-smokers; 4. Miller Class I-II (no interproximal attachment or CEJ loss); 5. probing depth (PD) \<3 mm; 6. GT ≥1 mm; 7. KGW ≥2 mm; 8. identifiable CEJ; 9. full-mouth plaque index (PI) \<20%(O'Leary et al., 1972) and gingival index (GI) score of 0(Löe, 1967) and 10. vital teeth to be treated.
Exclusion criteria
included: 1. smokers; 2. caries/restorations/abrasions in the treated area, furcation involvement; 3. contraindications to surgery; 4. pregnancy or lactation; 5. medications compromising healing; 6. surgery in the same region within 2 years; 7. bleeding disorders; 8. requirement for antibiotic prophylaxis; and 9. collagen allergy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of Complete Root Coverage | 12 Months | Percentage of CRC will be calculated as: (number of teeth achieving complete root coverage) ÷ (total treated teeth)\] × 100 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Recession depth | 12 month | RD will be measured from the cemento-enamel junction (CEJ) to the gingival margin and reported in millimeters (mm). |
| Probing depth | 12 months | Probing depth will be measured from the gingival margin to the base of the sulcus and reported in millimeters (mm). |
| Clinical attachment level | 12 months | Clinical attachment level will be measured from the cemento-enamel junction to the sulcus base and reported in millimeters (mm). |
| Keratinized gingiva width | 12 months | KGW will be measured from the mucogingival junction to the gingival margin and reported in millimeters (mm). |
| Percentage of Mean Root Coverage | 12 months | Percentage of root coverage will be calculated as: Percentage of root coverage: \[(preoperative recession depth - postoperative recession depth) ÷ preoperative recession depth\] × 100 |
| Postoperative Pain assessed using a Visual Analog Scale (VAS) | From the day of surgery through postoperative day 10 (11 days) | Postoperative pain will be assessed using a visual analog scale (VAS). Patients were asked to record the highest perceived pain each day from the day of surgery through the 10th postoperative day (total of 11 days). |
| Dentin Hypersensitivity Score assessed using Air Stimulus (HSS) | Baseline, 6 months, and 12 months | Dentin hypersensitivity will be assessed using a 1-second air stimulus applied to the buccal surface of the treated tooth. Patients rated the perceived hypersensitivity on a numerical rating scale ranging from 0 (no hypersensitivity) to 10 (unbearable hypersensitivity). |
| Pink Esthetic Score (PES) self-assessment | Baseline, 6 months, and 12 months | Esthetic outcomes will be evaluated using the Pink Esthetic Score (PES). Patients self-assessed gingival contour, gingival color, and overall esthetic appearance using a numerical rating scale ranging from 0 (unpleasant) to 10 (excellent). |
| Postoperative Analgesic Consumption | From the day of surgery through postoperative day 10 (11 days) | Postoperative analgesic consumption will be assessed by recording the total number of analgesic tablets taken by patients from the day of surgery through the 10th postoperative day. |
| Gingival Thickness | 12 months | Gingival thickness (GT) will beevaluated at the mid-facial aspect, 2 mm apical to the gingival margin in the attached gingiva or alveolar mucosa, using a #15 endodontic spreader (Bahadır Diş, Istanbul, Turkey) with a rubber stopper under local anesthesia and reported in milimeters. |
Countries
Turkey (Türkiye)
Outcome results
None listed