Periodontitis
Conditions
Keywords
periodontal maintenance, erythritol, powder air polishing
Brief summary
Periodontitis is a chronic, multifactorial disease primarily driven by the accumulation of bacterial deposits. Treatment involves the mechanical removal of the biofilm, traditionally performed by scaling and root planing (SRP). However, SRP is time-consuming and can cause irreversible damage to both hard and soft tissues as well as postoperative sensitivity. Consequently, adjunctive or alternative air-polishing devices have been developed. The objective of this study is to compare the clinical and microbiological efficacy of an erythritol-powder air-polishing device versus SRP in periodontal maintenance therapy.To evaluate patient-reported pain and treatment time for erythritol air-polishing versus SRP. A randomized clinical trial was designed and participants were randomly assigned to one of two groups: Intervention: Perio-Flow® (air + erythritol powder) and PIEZON PS®. Control: Ultrasonic debridement followed by SRP with Gracey curettes.At baseline and at six months, probing depth, clinical attachment level, and bleeding on probing were recorded. Saliva samples were collected to detect the most prevalent periodontal pathogens. Patient discomfort during treatment was measured by a visual analog scale, and procedure duration was timed.
Interventions
DEVICEAIRFLOW® Prophylaxis Master
Periodontal Maintenance with Erythritol Air Polisher in periodontal patients.
DEVICECavitron® ultrasonic scaler
Periodontal maintenance with ultrasonic scaler and manual curettes in periodontal patients.
Sponsors
Cardenal Herrera University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Patients who have received basic periodontal treatment between 3-6 months before the study.
Exclusion criteria
* Pregnant or breastfeeding patients. * Use of systemic antibiotics within 6 months prior to the study. * Patients who smoke more than 10 cigarettes/day. * Uncontrolled diabetic patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Improvement of clinical periodontal parameter: clinical attachment level | six months | Measurement of clinical attachment level in milimeters |
| Improvement of clinical periodontal parameter: probing depth | six months | Measurement of probing depth in milimeters |
| Improvement of clinical periodontal parameter: bleeding index | six months | Measurement of bleeding index in percentage. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in periodontal microbiome | Six months | We will present the following analyses: * Overall and differential abundance * Comparative relative inter-group community structure differences The overall and differential abundance of taxa will be analyzed using Kruskal Wallis non-parametric test. FDR Benjamini-Hochberg correction will be used to correct for multiple comparisons. Differences in community structure between experimental and control groups will be tested using Permanova. Permdisp test will be used to identify location vs. dispersion effects . The threshold for significance for all analyses will be set at p ≤ 0.05. 'BiodiversityR' version 2.11-1, 'PMCMR' version 4.3 and 'vegan' version 2.5-5 packages of the R software package version 36.6.0 (www.R-project.org) will be used. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Patient discomfort | Six months | Measurement of patient discomfort during the treatment by Visual Analogue Scale (VAS) Questionnaire (from no pain (score 0) to maximum pain imaginable (score 7)). |
Countries
Spain
Outcome results
None listed