Cardiac
Conditions
Brief summary
Blood flow restriction resistance exercise uses partial vascular occlusion of a limb during low weight resistance exercises to stimulate muscle strengthening and growth. This is commonly used during rehabilitation from an injury. Because blood flow in and out of the limbs is decreased, this may have consequences for blood flow through the heart. The purpose of this study will be to test cardiac dynamics during blood flow restriction resistance exercise to determine if cardiac blood flow is impacted. It is hypothesized that both non-BFR exercise and BFR exercise will increase heart rate shortening various cardiac cycle parameters, but BFR exercise will increase the isovolumetric contraction time vs non-BFR exercise due to an increase in total peripheral resistance. It is also hypothesized that BFR exercise will lower early ventricular filling parameters due to lower venous return.
Interventions
Blood flow in and out of the limb will be artificially with an occlusion cuff.
Sponsors
Montclair State University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Generally healthy
Exclusion criteria
* Uncontrolled hypertension * Peripheral vascular disease * Lymphedema * Sickle cell anemia * Heart failure * Stroke history * Heart attack history * Rheumatoid arthritis * Chronic kidney disease * Diabetes * Severe neuropathy * Any condition that may make blood flow restriction resistance exercise riskier like history of blood clots * Use of coagulant therapy * Susceptible to blood clots * Obesity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac cycle durations | During the intervention for approximately 10 minutes. |
| Ventricular filling | During intervention phase for approximately 10 minutes. |
Countries
United States
Contacts
CONTACTEvan Matthews
Outcome results
None listed