CT-Angiography Versus Angiogram as Ancillary Tests in the Determination of Death by Neurologic Criteria

A Comparison of Computed Tomography-Angiography Versus Four-vessel Angiography in the Determination of Brain Death

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07341490

Acronym

Tadaa

Enrollment

Registered

2026-01-14

Start date

2026-01-01

Completion date

2028-12-31

Last updated

2026-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infarction, Brain

Keywords

Cerebral infarction, Cerebral angiography, CT angiography, Brain Death, Diagnostic performance, Brain infarct

Brief summary

Diagnostic performance of a novel protocol for computed tomography-angiography, as ancillary test in the determination of complete cerebral infarction, in comparison to four vessel angiography.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults 18 years or older * Ongoing critical care due to severe acute brain injury * Four vessel angiography necessary for the determination of complete cerebral infarction, according to Swedish legislation

Exclusion criteria

* Treatment with extracorporeal membrane oxygenation (ECMO) * Radiologic examination by computed tomography deemed too challenging due to respiratory or circulatory instability, as determined by responsible clinician

Design outcomes

Primary

Measure	Time frame	Description
Diagnostic performance similar between computed tomography-angiography and four vessel angiography	Periprocedural	Sensitivity, specificity, positive predictive value, negative predictive value, inter- and intrarater variability.

Countries

Sweden

Contacts

CONTACTPeter C Rudberg, M.D. Ph.D.

peter.rudberg@ki.se+46-8-1237000

CONTACTAnja Rosén, M.D.

anja.rosen@ki.se+46-8-12370000

Outcome results