Pulmonary Mucormycosis
Conditions
Keywords
Pulmonary Mucormycosis, Fungal infections
Brief summary
Invasive pulmonary fungal infections caused by Mucorales are rare but severe and rapidly progressive, affecting immunocompromised patients. The role of chest imaging in their diagnosis is well established in the 2020 EORTC/MSGERC criteria, and its use is almost systematic. However, the progression of lung parenchymal involvement and any potential prognostic radiological patterns in the follow-up of these infections are less well understood. This research aims to identify imaging characteristics predictive of favorable or unfavorable outcomes in infected patients, in order to better tailor follow-up and therapeutic options.
Interventions
None listed
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged 18 years or older * Treated at Strasbourg University Hospital between January 1, 2009, and June 3, 2025 * With a diagnosis of probable or proven invasive pulmonary infection with Mucorales according to the 2020 EORTC/MSGERC criteria * Having undergone at least one CT scan including the thoracic region
Exclusion criteria
* No CT scan including the thoracic region * No diagnosis of probable or proven invasive pulmonary infection with Mucorales (EORTC/MSGERC 2020 criteria)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Death rate in patients with probable or proven invasive Mucorales infection | Day 15 after infection | Death rate at day 15 in patients with probable or proven invasive Mucorales infection |
Countries
France
Contacts
Primary Contactbaptiste Hoellinger, MD
Outcome results
None listed