Molar-Incisor Hypomineralization (MIH)
Conditions
Keywords
Pediatric Dentistry, MIH, Occlusal Balance, Electromyography, T-Scan, sEMG, Molar-Incisor Hypomineralization, Occlusal Force Distribution, Glass-Hybrid Restoration
Brief summary
This prospective pilot study evaluates the effect of restoring symptomatic, carious molar-incisor hypomineralization (MIH)-affected permanent molars using a glass-hybrid restorative material on occlusal force distribution and masticatory muscle activity. Digital occlusal analysis using the T-Scan system and surface electromyography (sEMG) recordings of the masseter and anterior temporalis muscles are performed before treatment and three months after restoration. Hypersensitivity is assessed using the Schiff Cold Air Sensitivity Scale.
Detailed description
This single-arm prospective pilot study investigates whether restorative rehabilitation of MIH-affected permanent molars leads to functional improvements in occlusal balance and neuromuscular activity. Children aged 7-13 years with symptomatic MIH requiring restorative treatment undergo standardized glass-hybrid restorations. Functional occlusal analysis is conducted using the T-Scan Novus system to assess lateral occlusal force distribution, while bilateral surface electromyography (sEMG) evaluates masseter and temporalis muscle activity during maximum voluntary clenching. Dentin hypersensitivity is assessed using the Schiff Cold Air Sensitivity Scale. Pre- and post-treatment outcomes are compared to explore early functional adaptation following MIH rehabilitation.
Interventions
PROCEDUREGlass-Hybrid Restoration
Selective caries removal followed by bulk-fill glass-hybrid restoration of MIH-affected first permanent molars using Equia Forte®. The procedure is performed by a calibrated pediatric dentist according to the manufacturer's instructions. Occlusion is checked and adjusted after restoration prior to functional assessments.
Sponsors
Marmara University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
7 Years to 13 Years
Healthy volunteers
No
Inclusion criteria
* Children aged 7 to 13 years * Diagnosis of molar-incisor hypomineralization (MIH) according to the criteria of Ghanim et al. * Presence of at least two MIH-affected first permanent molars with post-eruptive enamel breakdown requiring restorative treatment * Presence of dentin hypersensitivity in the affected molars * Ability to comply with T-Scan and surface electromyography (sEMG) recording procedures * Written informed consent obtained from parents or legal guardians, and assent from the child *
Exclusion criteria
* Previous or ongoing orthodontic treatment * Presence of craniofacial anomalies or syndromes * Diagnosis of temporomandibular disorders * Parafunctional habits (e.g., bruxism) * Clinically evident facial asymmetry * Malocclusions such as crossbite or open bite * Systemic diseases or medications affecting neuromuscular function -Inability to cooperate with functional assessment procedures -
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lateral Occlusal Force Distribution (LOFD) | Baseline and 3 months post-treatment | Change in lateral occlusal force distribution assessed using the T-Scan digital occlusal analysis system during maximum voluntary clenching. The primary variable is the absolute deviation from ideal 50-50 bilateral force distribution, calculated at baseline and 3 months after glass-hybrid restoration. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Masticatory Muscle Activity Symmetry | Baseline and 3 months post-treatment | right-left asymmetry indices of the masseter and anterior temporalis muscles measured using surface electromyography (sEMG) during maximum voluntary clenching. |
| Dentin Hypersensitivity | Baseline and 3 months post-treatment | Dentin hypersensitivity of MIH-affected molars assessed using the Schiff Cold Air Sensitivity Scale following an air-blast stimulus. |
Countries
Turkey (Türkiye)
Outcome results
None listed