Cardiac Failure, Respiratory Failure
Conditions
Keywords
Cardiac Failure, Respiratory Failure
Brief summary
Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.
Interventions
None listed
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital. * Implanted with veno-arterial or veno-venous ECMO within the previous 24 hours.
Exclusion criteria
* Subject who has expressed their opposition to participating in the study. * Subject under legal protection. * Subject under guardianship or curatorship.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Proportional Changes in the Different Platelet Populations (native, proaggregating, procoagulant, or apoptotic) | Days 1, 3, and 7 after the initiation of ECMO treatment. | Proportional Changes in the Different Platelet Populations (native, proaggregating, procoagulant, or apoptotic) on Days 1, 3, and 7 after the initiation of ECMO treatment. |
Countries
France
Contacts
Primary ContactCharles TACQUARD, MD, PhD
Outcome results
None listed