Skip to content

Optimizing the Management of OSA in Children With Down Syndrome

Current Status Assessment for the Development of a Protocol to Optimize the Management of Obstructive Sleep Apnea (OSA) in Children With Down Syndrome

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07334444
Acronym
SAOS-21
Enrollment
30
Registered
2026-01-12
Start date
2025-03-19
Completion date
2026-06-19
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive Sleep Apnea

Keywords

Obstructive Sleep Apnea of Child, Down syndrome

Brief summary

The objective of this retrospective descriptive study is to assess current practices for the screening and surgical treatment of OSA in children with Down syndrome at the Strasbourg University Hospital and to disseminate a management algorithm in France.

Interventions

None listed

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
0 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

* Child with Down syndrome, * Aged between 0 and 17 years, * Having been seen for an ENT consultation at the University Hospital or the Sleep Center of the University Hospital of Strasbourg between January 1, 2019, and December 31, 2024

Exclusion criteria

\- Presence of a written objection in the medical file of the subject (and/or their representative) to the reuse of their data for scientific research purposes.

Design outcomes

Primary

MeasureTime frameDescription
Apnea-hypopnea index (AHI) before and after surgery.Day 1 before surgery and Day 1 after surgeryThe AHI is a number that indicates how many times per hour breathing is abnormal during sleep. It adds up: * Apneas → breathing stops completely * Hypopneas → breathing becomes much shallower Scores: * AHI \< 5 → normal * AHI between 5 and 15 → mild impairment * AHI between 15 and 30 → moderate impairment

Countries

France

Contacts

Primary ContactGuillaume TRAU, MD
guillaume.trau@chru-strasbourg.fr33 3 88 12 76 44

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026