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The Application of Extracellular Vesicle Detection in Gastric Juice Based on Metamaterial Sensing in the Diagnosis of Gastric Cancer and Related Diseases

The Application of Extracellular Vesicle Detection in Gastric Juice Based on Metamaterial Sensing in the Diagnosis of Gastric Cancer and Related Diseases

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07332104
Enrollment
100
Registered
2026-01-12
Start date
2025-12-15
Completion date
2026-12-15
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancer (Diagnosis), Gastric Cancer (GC)

Keywords

Gastric cancer, Extracellular vesicles

Brief summary

After obtaining informed consent from the patients, all the medical history and treatment records of the patients who underwent gastroscopy since the onset of the disease, as well as gastric fluid samples, including laboratory and imaging data, were collected and recorded. The medical history and treatment records and gastric fluid samples were analyzed.

Interventions

DIAGNOSTIC_TESTIn vitro surface plasmon resonance detection

Gastric juice from patients was removed for isolation of extracellular vesicles and surface plasmon resonance detection in vitro

Sponsors

Beijing Friendship Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
40 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients underwent gastroscopy and treatment at the Endoscopy Center of Beijing Friendship Hospital, Capital Medical University, and received pathological biopsy. * Previous gastroscopy suggested the possibility of lesions. * No previous history of gastrointestinal cancer.

Exclusion criteria

* Patients could not cooperate with the examination or had contraindications to endoscopy. * Previous history of gastrointestinal tumors, gastrointestinal surgery, physical and chemical injuries of the gastrointestinal tract. * Severe bile reflux. * Take simethicone and other defoaming agents before examination. * Patients with serious diseases of heart, lung, kidney, brain, blood and other important organs.

Design outcomes

Primary

MeasureTime frame
Surface plasmon resonance(SPR) detection of extracellular vesicles in gastric juice of patients with gastric cancer has large shift and spectral changesbaseline

Contacts

Primary ContactHao-Su Zhan, Dr.
1509082764@qq.com13565915192

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026