Pityriasis Versicolor
Conditions
Brief summary
Comparative efficacy of topical 1% clotrimazole vs oral itraconazole in the treatment of pityriasis versicolor -Randomized control trial
Interventions
DRUGTopical 1 % clotrimazole twice daily 2 weeks
Topical 1% clotrimazole twice daily for 2 weeks
DRUGOral itraconazole 200mg daily for 5 days
Oral itraconazole 200mg daily for 5 days
Sponsors
Combined Military Hospital Abbottabad
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
15 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Age (15-50 years) * Both genders * Sufferers of Pityriasis versicolor ( Determined by scale , erythema and pruritus)
Exclusion criteria
* Pt with history of antifungals in last one month * Pt on immunosuppressants or steroid therapy * Pregnant and lactating women * Pt with chronic medical conditions ( Diabetes and hypertension)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentile efficacy of topical versus oral antifungal in the treatment of pityriasis versicolor | 3 months | Data analysis will be performed using SPSS version 20. The quantitative variable (age, BMI and duration of PV) will be presented as mean ± standard deviation (SD) or median interquartile range (IQR) after checking normality of data by using Shapiro-Wilk test. Frequency and percentages will be used for categorical variables (gender, severity of PV, area of residence, level of education and efficacy). Efficacy will be compared between groups using Chi-square or Fisher exact test. Efficacy will be stratified by age, gender, BMI, duration of PV and severity of PV to deal with effect modifiers. Post-stratification chi-square test or Fischer exact test will be used as test of significance. A p-value of ≤ 0.05 will be considered statistically significant. |
Contacts
Primary ContactZaeema Aman, MBBS
Backup ContactAli Amar, MBBS, FCPS
Outcome results
None listed